U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CAPN12 calpain 12 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693804, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CAPN12provided by VGNC
    Official Full Name
    calpain 12provided by VGNC
    Primary source
    VGNC:VGNC:70473
    See related
    Ensembl:ENSMMUG00000006431
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CAPN12 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (37982470..38016182, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (34469068..34489962, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 1 Neighboring gene eukaryotic translation initiation factor 3 subunit K Neighboring gene actinin alpha 4 Neighboring gene galectin-7 Neighboring gene galectin-7

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    calpain-12

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      37982470..38016182 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840017.1 → XP_028695850.1  calpain-12 isoform X2

      UniProtKB/TrEMBL
      A0A1D5RDX0, A0A5F7ZJ58
      Related
      ENSMMUP00000058513.2, ENSMMUT00000064875.2
      Conserved Domains (4) summary
      cd00214
      Location:332 → 510
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:531 → 559
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:57 → 319
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:531 → 699
      EFh_PEF; The penta-EF hand (PEF) family

    2. XM_028840023.1 → XP_028695856.1  calpain-12 isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZJ58
      Conserved Domains (4) summary
      cd00214
      Location:187 → 365
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:386 → 414
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:1 → 174
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:386 → 554
      EFh_PEF; The penta-EF hand (PEF) family

    3. XM_028840020.1 → XP_028695853.1  calpain-12 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZJ58
      Related
      ENSMMUP00000064649.1, ENSMMUT00000109824.1
      Conserved Domains (4) summary
      cd00214
      Location:261 → 439
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:460 → 488
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:2 → 248
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:460 → 628
      EFh_PEF; The penta-EF hand (PEF) family

    4. XM_015123862.2 → XP_014979348.2  calpain-12 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZJ58
      Conserved Domains (4) summary
      cd00214
      Location:261 → 439
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:460 → 488
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:2 → 248
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:460 → 628
      EFh_PEF; The penta-EF hand (PEF) family

    5. XM_015123863.2 → XP_014979349.2  calpain-12 isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZJ58
      Conserved Domains (4) summary
      cd00214
      Location:187 → 365
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:386 → 414
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:1 → 174
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:386 → 554
      EFh_PEF; The penta-EF hand (PEF) family

    6. XM_028840019.1 → XP_028695852.1  calpain-12 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZJ58
      Conserved Domains (4) summary
      cd00214
      Location:261 → 439
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:460 → 488
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:2 → 248
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:460 → 628
      EFh_PEF; The penta-EF hand (PEF) family

    7. XM_028840018.1 → XP_028695851.1  calpain-12 isoform X3

      UniProtKB/TrEMBL
      G7NNI9
      Conserved Domains (4) summary
      cd15897
      Location:478 → 506
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:46 → 339
      Peptidase_C2; Calpain family cysteine protease
      cl00165
      Location:349 → 457
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cl25352
      Location:478 → 646
      EFh_PEF; The penta-EF hand (PEF) family

    8. XM_015123864.2 → XP_014979350.2  calpain-12 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZJ58, F7HSF8
      Related
      ENSMMUP00000008472.4, ENSMMUT00000009015.4
      Conserved Domains (4) summary
      cd00214
      Location:352 → 530
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cd15897
      Location:551 → 579
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:46 → 339
      Peptidase_C2; Calpain family cysteine protease
      cl25352
      Location:551 → 719
      EFh_PEF; The penta-EF hand (PEF) family

    9. XM_028840021.1 → XP_028695854.1  calpain-12 isoform X5

      UniProtKB/TrEMBL
      G7NNI9
      Conserved Domains (4) summary
      cd15897
      Location:478 → 506
      EFh_PEF; EF-hand motif [structural motif]
      pfam00648
      Location:46 → 339
      Peptidase_C2; Calpain family cysteine protease
      cl00165
      Location:349 → 457
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
      cl25352
      Location:478 → 553
      EFh_PEF; The penta-EF hand (PEF) family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.