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    PIAS2 protein inhibitor of activated STAT 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696737, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PIAS2provided by VGNC
    Official Full Name
    protein inhibitor of activated STAT 2provided by VGNC
    Primary source
    VGNC:VGNC:75815
    See related
    Ensembl:ENSMMUG00000004498
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PIAS2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (35508117..35616083)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (35783920..35878238, complement)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene katanin catalytic subunit A1 like 2 Neighboring gene elongin-A3-like Neighboring gene elongin-A3-like Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Neighboring gene lipoxygenase homology PLAT domains 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 SUMO-protein ligase PIAS2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      35508117..35616083
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028837784.1 → XP_028693617.1  E3 SUMO-protein ligase PIAS2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Related
      ENSMMUP00000053291.2, ENSMMUT00000066878.2
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:343 → 390
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:147 → 291
      PINIT; PINIT domain

    2. XM_028837785.1 → XP_028693618.1  E3 SUMO-protein ligase PIAS2 isoform X2

      UniProtKB/TrEMBL
      G7MPS1
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:343 → 390
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:147 → 296
      PINIT; PINIT domain

    3. XM_028837786.1 → XP_028693619.1  E3 SUMO-protein ligase PIAS2 isoform X3

      UniProtKB/TrEMBL
      G7MPS1, H9EPS0
      Related
      ENSMMUP00000068967.1, ENSMMUT00000105520.1
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:343 → 390
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:147 → 296
      PINIT; PINIT domain

    4. XM_028837789.1 → XP_028693622.1  E3 SUMO-protein ligase PIAS2 isoform X5

      UniProtKB/TrEMBL
      A0A1D5QZ09, H9EPS1
      Related
      ENSMMUP00000070831.1, ENSMMUT00000082661.1
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:343 → 390
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:147 → 291
      PINIT; PINIT domain

    5. XM_028837790.1 → XP_028693623.1  E3 SUMO-protein ligase PIAS2 isoform X6

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Conserved Domains (3) summary
      smart00513
      Location:11 → 45
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:343 → 390
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:147 → 296
      PINIT; PINIT domain

    6. XM_028837788.1 → XP_028693621.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Conserved Domains (3) summary
      smart00513
      Location:2 → 36
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:334 → 381
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:138 → 282
      PINIT; PINIT domain

    7. XM_028837787.1 → XP_028693620.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Conserved Domains (3) summary
      smart00513
      Location:2 → 36
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:334 → 381
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:138 → 282
      PINIT; PINIT domain

    8. XM_015121875.2 → XP_014977361.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Conserved Domains (3) summary
      smart00513
      Location:2 → 36
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:334 → 381
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:138 → 282
      PINIT; PINIT domain

    9. XM_015121877.2 → XP_014977363.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Conserved Domains (3) summary
      smart00513
      Location:2 → 36
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:334 → 381
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:138 → 282
      PINIT; PINIT domain

    10. XM_015121876.2 → XP_014977362.1  E3 SUMO-protein ligase PIAS2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QZ09
      Conserved Domains (3) summary
      smart00513
      Location:2 → 36
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd16790
      Location:334 → 381
      SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
      pfam14324
      Location:138 → 282
      PINIT; PINIT domain

    RNA

    1. XR_003724446.1 RNA Sequence

    2. XR_003724447.1 RNA Sequence

    3. XR_003724448.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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