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    DCAF4L2 DDB1 and CUL4 associated factor 4 like 2 [ Homo sapiens (human) ]

    Gene ID: 138009, updated on 9-Dec-2024

    Summary

    Official Symbol
    DCAF4L2provided by HGNC
    Official Full Name
    DDB1 and CUL4 associated factor 4 like 2provided by HGNC
    Primary source
    HGNC:HGNC:26657
    See related
    Ensembl:ENSG00000176566 MIM:620421; AllianceGenome:HGNC:26657
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    WDR21C
    Summary
    Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See DCAF4L2 in Genome Data Viewer
    Location:
    8q21.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (87870747..87874015, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (88994111..88997374, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (88882975..88886243, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene SOX5 pseudogene 1 Neighboring gene zinc finger protein 773 pseudogene Neighboring gene uncharacterized LOC124901972 Neighboring gene uncharacterized LOC105375628

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    DDB1- and CUL4-associated factor 4-like protein 2
    Names
    WD repeat domain 21C
    WD repeat-containing protein 21C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152418.4NP_689631.1  DDB1- and CUL4-associated factor 4-like protein 2

      See identical proteins and their annotated locations for NP_689631.1

      Status: VALIDATED

      Source sequence(s)
      AC005066, AK093094, AL833507, BC035011
      Consensus CDS
      CCDS6245.1
      UniProtKB/Swiss-Prot
      Q8NA75
      Related
      ENSP00000316496.3, ENST00000319675.5
      Conserved Domains (3) summary
      COG2319
      Location:186300
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:223267
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:269369
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      87870747..87874015 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      88994111..88997374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)