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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001282129.2 → NP_001269058.1 protein phosphatase Slingshot homolog 2 isoform 1
See identical proteins and their annotated locations for NP_001269058.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB099290, AC104982, AI609950, AK296413, DA749059
- Consensus CDS
-
CCDS74024.1
- UniProtKB/TrEMBL
- B4DK64, F5H527
- Related
- ENSP00000444743.1, ENST00000540801.6
- Conserved Domains (3) summary
-
- cd11652
Location:38 → 263
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:335 → 470
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:278 → 329
- DEK_C; DEK C terminal domain
-
NM_001282130.2 → NP_001269059.1 protein phosphatase Slingshot homolog 2 isoform 3
See identical proteins and their annotated locations for NP_001269059.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks multiple coding exons and contains an alternate 3' exon, resulting in a distinct 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC104564, AC104982, BC008941, DA749059
- UniProtKB/Swiss-Prot
-
Q76I76
- Conserved Domains (1) summary
-
- cd11652
Location:3 → 178
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
-
NM_001282131.2 → NP_001269060.1 protein phosphatase Slingshot homolog 2 isoform 4
See identical proteins and their annotated locations for NP_001269060.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains multiple differences in the UTRs and coding region, compared to variant 1, including the lack of multiple 5' and 3' coding exons. It represents use of an internal promoter and initiates translation at an alternate start codon. The encoded isoform (4) is shorter and has distinct N- and C- termini, compared to isoform 1.
- Source sequence(s)
-
AC104564, BC008941, BC011636, DA861985
- Consensus CDS
-
CCDS92286.1
- UniProtKB/TrEMBL
-
A0A3B3ITS1
- Related
- ENSP00000497894.1, ENST00000324677.12
- Conserved Domains (1) summary
-
- cd11652
Location:37 → 185
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
-
NM_033389.3 → NP_203747.2 protein phosphatase Slingshot homolog 2 isoform 2
See identical proteins and their annotated locations for NP_203747.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AB099290, AC104564, AI609950, DA749059
- Consensus CDS
-
CCDS11253.1
- UniProtKB/Swiss-Prot
- Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8
- UniProtKB/TrEMBL
-
B4DK64
- Related
- ENSP00000269033.3, ENST00000269033.7
- Conserved Domains (3) summary
-
- cd11652
Location:3 → 236
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:308 → 443
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:251 → 302
- DEK_C; DEK C terminal domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
29625938..29930228 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047436967.1 → XP_047292923.1 protein phosphatase Slingshot homolog 2 isoform X3
- UniProtKB/Swiss-Prot
- Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8
- UniProtKB/TrEMBL
-
B4DK64
-
XM_005258058.4 → XP_005258115.1 protein phosphatase Slingshot homolog 2 isoform X1
See identical proteins and their annotated locations for XP_005258115.1
- UniProtKB/TrEMBL
- B4DK64, F5H527
- Conserved Domains (3) summary
-
- cd11652
Location:38 → 263
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:335 → 470
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:278 → 329
- DEK_C; DEK C terminal domain
-
XM_047436968.1 → XP_047292924.1 protein phosphatase Slingshot homolog 2 isoform X11
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_011525407.1 → XP_011523709.1 protein phosphatase Slingshot homolog 2 isoform X6
See identical proteins and their annotated locations for XP_011523709.1
- UniProtKB/TrEMBL
-
A0A3B3IS79
- Conserved Domains (3) summary
-
- cd11652
Location:17 → 160
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:232 → 367
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:175 → 226
- DEK_C; DEK C terminal domain
-
XM_005258059.3 → XP_005258116.1 protein phosphatase Slingshot homolog 2 isoform X2
See identical proteins and their annotated locations for XP_005258116.1
- UniProtKB/TrEMBL
-
A0A3B3IS79
- Related
- ENSP00000497148.1, ENST00000649863.1
- Conserved Domains (3) summary
-
- cd11652
Location:37 → 243
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:315 → 450
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:258 → 309
- DEK_C; DEK C terminal domain
-
XM_047436969.1 → XP_047292925.1 protein phosphatase Slingshot homolog 2 isoform X6
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_006722149.5 → XP_006722212.1 protein phosphatase Slingshot homolog 2 isoform X5
- UniProtKB/TrEMBL
-
A0A3B3IS79
- Conserved Domains (3) summary
-
- cd11652
Location:14 → 214
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:286 → 421
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:229 → 280
- DEK_C; DEK C terminal domain
-
XM_011525404.3 → XP_011523706.1 protein phosphatase Slingshot homolog 2 isoform X4
- UniProtKB/TrEMBL
-
A0A3B3IS79
- Conserved Domains (3) summary
-
- cd11652
Location:18 → 218
- SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
- cd00127
Location:290 → 425
- DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
- pfam08766
Location:233 → 284
- DEK_C; DEK C terminal domain
-
XM_005258060.4 → XP_005258117.1 protein phosphatase Slingshot homolog 2 isoform X7
- UniProtKB/TrEMBL
-
B3KRE8
-
XM_047436970.1 → XP_047292926.1 protein phosphatase Slingshot homolog 2 isoform X9
-
XM_017025253.3 → XP_016880742.1 protein phosphatase Slingshot homolog 2 isoform X8
-
XM_047436971.1 → XP_047292927.1 protein phosphatase Slingshot homolog 2 isoform X10
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
30568840..30873583 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054317622.1 → XP_054173597.1 protein phosphatase Slingshot homolog 2 isoform X3
- UniProtKB/TrEMBL
-
B4DK64
-
XM_054317620.1 → XP_054173595.1 protein phosphatase Slingshot homolog 2 isoform X1
- UniProtKB/TrEMBL
-
B4DK64
-
XM_054317627.1 → XP_054173602.1 protein phosphatase Slingshot homolog 2 isoform X6
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_054317626.1 → XP_054173601.1 protein phosphatase Slingshot homolog 2 isoform X6
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_054317625.1 → XP_054173600.1 protein phosphatase Slingshot homolog 2 isoform X6
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_054317621.1 → XP_054173596.1 protein phosphatase Slingshot homolog 2 isoform X2
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_054317624.1 → XP_054173599.1 protein phosphatase Slingshot homolog 2 isoform X5
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_054317623.1 → XP_054173598.1 protein phosphatase Slingshot homolog 2 isoform X4
- UniProtKB/TrEMBL
-
A0A3B3IS79
-
XM_054317628.1 → XP_054173603.1 protein phosphatase Slingshot homolog 2 isoform X7
- UniProtKB/TrEMBL
-
B3KRE8
-
XM_054317630.1 → XP_054173605.1 protein phosphatase Slingshot homolog 2 isoform X9
-
XM_054317629.1 → XP_054173604.1 protein phosphatase Slingshot homolog 2 isoform X8
-
XM_054317631.1 → XP_054173606.1 protein phosphatase Slingshot homolog 2 isoform X10