Tmem147 transmembrane protein 147 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tmem147provided by MGI
Official Full Name: transmembrane protein 147provided by MGI
Primary source: MGI:MGI:1915011
See related: Ensembl:ENSMUSG00000006315 AllianceGenome:MGI:1915011
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Nifie14; 2010004E11Rik; 5033425B17Rik
Summary: Predicted to enable ribosome binding activity. Predicted to be involved in multi-pass transmembrane protein insertion into ER membrane and protein localization to nuclear inner membrane. Predicted to be located in nuclear membrane and plasma membrane. Predicted to be part of multi-pass translocon complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in genitourinary system. Orthologous to human TMEM147 (transmembrane protein 147). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in kidney adult (RPKM 145.9), adrenal adult (RPKM 135.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B1; 7 19.23 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (30427126..30428959, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (30727701..30729534, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ribosome binding	ISO Inferred from Sequence Orthology more info
enables ribosome binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in multi-pass transmembrane protein insertion into ER membrane	ISO Inferred from Sequence Orthology more info
involved_in multi-pass transmembrane protein insertion into ER membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization to nuclear inner membrane	ISO Inferred from Sequence Orthology more info
involved_in protein localization to nuclear inner membrane	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of multi-pass translocon complex	ISO Inferred from Sequence Orthology more info
located_in nuclear membrane	ISO Inferred from Sequence Orthology more info
located_in nuclear membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: BOS complex subunit TMEM147

Names: seven transmembrane domain protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027215.2 → NP_081491.2 BOS complex subunit TMEM147

See identical proteins and their annotated locations for NP_081491.2

Status: VALIDATED

Source sequence(s)

AK010168, AK160267

Consensus CDS

CCDS39890.1

UniProtKB/Swiss-Prot

Q8CI89, Q9CQG6, Q9D8F0

UniProtKB/TrEMBL

A0A140LJ56, B2RVQ1

Related

ENSMUSP00000006478.9, ENSMUST00000006478.10

Conserved Domains (1) summary

pfam09767
Location:2 → 158

DUF2053; Predicted membrane protein (DUF2053)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

30427126..30428959 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036153426.1 → XP_036009319.1 BOS complex subunit TMEM147 isoform X1

UniProtKB/TrEMBL

A0A140LIQ8

Related

ENSMUSP00000146918.2, ENSMUST00000209065.2

Conserved Domains (1) summary

pfam09767
Location:1 → 106

DUF2053; Predicted membrane protein (DUF2053)