Ighg Immunoglobulin heavy chain (gamma polypeptide) [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ighgprovided by MGI
Official Full Name: Immunoglobulin heavy chain (gamma polypeptide)provided by MGI
Primary source: MGI:MGI:2144967
See related: AllianceGenome:MGI:2144967
Gene type: protein coding
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: IGHG2A
Summary: Enables immunoglobulin receptor binding activity. Predicted to be involved in antibacterial humoral response and complement activation, classical pathway. Predicted to be located in extracellular space. Predicted to be part of IgG immunoglobulin complex and immunoglobulin complex, circulating. Orthologous to several human genes including IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker)); IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)); and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker)). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: not in current annotation release
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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables Fc-gamma receptor I complex binding	ISO Inferred from Sequence Orthology more info
enables antigen binding	IBA Inferred from Biological aspect of Ancestor more info
enables immunoglobulin receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables immunoglobulin receptor binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in antibacterial humoral response	IBA Inferred from Biological aspect of Ancestor more info
involved_in complement activation, classical pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of IgG immunoglobulin complex	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
part_of immunoglobulin complex, circulating	IBA Inferred from Biological aspect of Ancestor more info

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The following Reference Sequences have been suppressed. Explain

NM_212451.1: Suppressed sequence

Description

NM_212451.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.