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    Mycbp2 MYC binding protein 2, E3 ubiquitin protein ligase [ Mus musculus (house mouse) ]

    Gene ID: 105689, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Mycbp2provided by MGI
    Official Full Name
    MYC binding protein 2, E3 ubiquitin protein ligaseprovided by MGI
    Primary source
    MGI:MGI:2179432
    See related
    Ensembl:ENSMUSG00000033004 AllianceGenome:MGI:2179432
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pam; Phr1; C130061D10Rik
    Summary
    Enables identical protein binding activity. Involved in several processes, including central nervous system projection neuron axonogenesis; circadian regulation of gene expression; and positive regulation of protein ubiquitination. Acts upstream of or within several processes, including branchiomotor neuron axon guidance; negative regulation of protein catabolic process; and regulation of cytoskeleton organization. Located in axon and microtubule cytoskeleton. Is expressed in nervous system and neural retina. Orthologous to human MYCBP2 (MYC binding protein 2). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 20.7), cerebellum adult (RPKM 15.2) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mycbp2 in Genome Data Viewer
    Location:
    14 E2.3; 14 51.79 cM
    Exon count:
    88
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (103350847..103584276, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (103113411..103346840, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37499 Neighboring gene STARR-positive B cell enhancer ABC_E11579 Neighboring gene STARR-seq mESC enhancer starr_37500 Neighboring gene ceroid-lipofuscinosis, neuronal 5 Neighboring gene F-box and leucine-rich repeat protein 3 Neighboring gene STARR-seq mESC enhancer starr_37501 Neighboring gene RIKEN cDNA 1700087I21 gene Neighboring gene STARR-positive B cell enhancer mm9_chr14:103745967-103746268 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:103748726-103748913 Neighboring gene STARR-positive B cell enhancer ABC_E10839 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1. Sampathkumar P, et al. J Mol Biol, 2010 Apr 9. PMID 20156452, Free PMC Article
    2. Phr1 is required for proper retinocollicular targeting of nasal-dorsal retinal ganglion cells. Vo BQ, et al. Vis Neurosci, 2011 Mar. PMID 21324225
    3. The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction. Babetto E, et al. Cell Rep, 2013 May 30. PMID 23665224, Free PMC Article
    4. An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14. Hagarman JA, et al. Genesis, 2009 Jun. PMID 19391113
    5. The RCC1 domain of protein associated with Myc (PAM) interacts with and regulates KCC2. Garbarini N, et al. Cell Physiol Biochem, 2008. PMID 18769030, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. this study shows that Myc binding protein 2 suppresses M2-like phenotypes in macrophages during zymosan-induced inflammation in mice
      Title: Myc binding protein 2 suppresses M2-like phenotypes in macrophages during zymosan-induced inflammation in mice.
    2. nuclear localization of Ran was strongly increased in MYCBP2-deficient DRGs
      Title: MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia.
    3. Arf-bp1 and Pam are novel regulators of circadian gene expression that target Rev-erb alpha for degradation
      Title: E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.
    4. Mycbp2 and Robo2 were found to cooperate within a genetic network that has profound effects on axon guidance
      Title: The E3 ubiquitin ligase Mycbp2 genetically interacts with Robo2 to modulate axon guidance in the mouse olfactory system.
    5. Phr1 is identified as a key regulator of a core axon degeneration program that balances axon survival and loss in various neuronal cell types.
      Title: The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction.
    6. The ubiquitin ligase complex containing Pam-Fbxo45 likely targets additional synaptic and axonal proteins, which may explain the overlapping neurodevelopmental defects observed in Phr1 and Fbxo45 deficiency.
      Title: The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.
    7. These results show that Phr1 is an essential regulator of retinal ganglion cell projection during both dLGN and SC topographic map development.
      Title: Phr1 is required for proper retinocollicular targeting of nasal-dorsal retinal ganglion cells.
    8. p38 MAPK activation can inhibit activity-induced ion channel internalization and MYCBP2 regulates internalization of TRPV1 in peripheral sensory neurons as well as duration of thermal hyperalgesia through p38 MAPK
      Title: The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1) internalization through inhibition of p38 MAPK signaling.
    9. Structures of both the first and second PHR domains of Mus musculus (mouse) Phr1 (MYC binding protein 2, Mycbp2) have been determined, revealing a novel beta sandwich fold composed of 11 antiparallel beta-strands.
      Title: Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1.
    10. Results show that a loss-of-function allele of Phr1 resulting in respiratory distress at birth.
      Title: An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14.
    Submit: New GeneRIF Correction See all GeneRIFs (13)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables small GTPase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within branchiomotor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell morphogenesis involved in neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within central nervous system projection neuron axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in central nervous system projection neuron axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in circadian regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in circadian regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuromuscular process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of synaptic assembly at neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MYCBP2
    Names
    Myc-binding protein 2
    RING-type E3 ubiquitin transferase MYCBP2
    pam, highwire, rpm 1
    pam/highwire/rpm-1 protein
    probable E3 ubiquitin-protein ligase MYCBP2
    protein Magellan
    protein associated with Myc
    NP_997098.2
    XP_006518455.1
    XP_011243195.1
    XP_011243196.1
    XP_011243197.1
    XP_011243198.1
    XP_011243199.1
    XP_011243200.1
    XP_011243201.1
    XP_011243202.1
    XP_011243203.1
    XP_011243204.1
    XP_011243205.1
    XP_011243206.1
    XP_011243207.1
    XP_011243208.1
    XP_011243209.1
    XP_017171266.1
    XP_017171267.1
    XP_017171268.1
    XP_017171269.1
    XP_017171271.1
    XP_017171272.1
    XP_017171273.1
    XP_017171274.1
    XP_017171275.1
    XP_017171276.1
    XP_017171277.1
    XP_017171278.1
    XP_017171279.1
    XP_017171280.1
    XP_017171281.1
    XP_017171282.1
    XP_017171283.1
    XP_030103457.1
    XP_030103458.1
    XP_030103459.1
    XP_030103460.1
    XP_030103461.1
    XP_036014271.1
    XP_036014272.1
    XP_036014273.1
    XP_036014275.1
    XP_036014276.1
    XP_036014278.1
    XP_036014279.1
    XP_036014280.1
    XP_036014281.1
    XP_036014282.1
    XP_036014283.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207215.2 → NP_997098.2  E3 ubiquitin-protein ligase MYCBP2

      Status: VALIDATED

      Source sequence(s)
      AC114410, AC114585, AY325887, BC059257
      Consensus CDS
      CCDS49559.1
      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Related
      ENSMUSP00000124710.2, ENSMUST00000159855.8
      Conserved Domains (6) summary
      smart00557
      Location:2389 → 2440
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1724 → 1879
      PHR; PHR domain
      pfam13540
      Location:943 → 971
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4494 → 4547
      zf-RING_2; Ring finger domain
      cl02148
      Location:3819 → 3911
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      103350847..103584276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158378.1 → XP_036014271.1  E3 ubiquitin-protein ligase MYCBP2 isoform X7

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (9) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4539 → 4593
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:4373 → 4421
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3862 → 3954
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1235 → 1385
      PHR; PHR domain
      pfam08239
      Location:2472 → 2534
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:2389 → 2440
      Filamin; Filamin/ABP280 repeat

    2. XM_011244896.3 → XP_011243198.1  E3 ubiquitin-protein ligase MYCBP2 isoform X5

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4541 → 4595
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1726 → 1881
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4375 → 4423
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3864 → 3956
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2391 → 2442
      Filamin; Filamin/ABP280 repeat

    3. XM_017315794.2 → XP_017171283.1  E3 ubiquitin-protein ligase MYCBP2 isoform X47

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4345 → 4399
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4179 → 4227
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3671 → 3763
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    4. XM_017315789.2 → XP_017171278.1  E3 ubiquitin-protein ligase MYCBP2 isoform X33

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4400 → 4454
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4234 → 4282
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3723 → 3815
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    5. XM_011244906.3 → XP_011243208.1  E3 ubiquitin-protein ligase MYCBP2 isoform X30

      UniProtKB/TrEMBL
      F6SMY7
      Related
      ENSMUSP00000124601.2, ENSMUST00000160758.8
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4423 → 4477
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4257 → 4305
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3746 → 3838
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    6. XM_017315783.2 → XP_017171272.1  E3 ubiquitin-protein ligase MYCBP2 isoform X21

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4475 → 4529
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4309 → 4357
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3798 → 3890
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    7. XM_036158379.1 → XP_036014272.1  E3 ubiquitin-protein ligase MYCBP2 isoform X12

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (9) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4509 → 4563
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:4343 → 4391
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3832 → 3924
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1235 → 1385
      PHR; PHR domain
      pfam08239
      Location:2475 → 2537
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    8. XM_030247598.1 → XP_030103458.1  E3 ubiquitin-protein ligase MYCBP2 isoform X26

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4448 → 4502
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4282 → 4330
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3771 → 3863
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    9. XM_036158380.1 → XP_036014273.1  E3 ubiquitin-protein ligase MYCBP2 isoform X19

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (9) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4482 → 4536
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:4316 → 4364
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3805 → 3897
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1235 → 1385
      PHR; PHR domain
      pfam08239
      Location:2475 → 2537
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    10. XM_017315779.2 → XP_017171268.1  E3 ubiquitin-protein ligase MYCBP2 isoform X16

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4500 → 4554
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4334 → 4382
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3823 → 3915
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    11. XM_011244895.3 → XP_011243197.1  E3 ubiquitin-protein ligase MYCBP2 isoform X3

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4542 → 4596
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1727 → 1882
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4376 → 4424
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3865 → 3957
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2392 → 2443
      Filamin; Filamin/ABP280 repeat

    12. XM_017315793.2 → XP_017171282.1  E3 ubiquitin-protein ligase MYCBP2 isoform X39

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4347 → 4401
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4181 → 4229
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3673 → 3765
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    13. XM_017315792.2 → XP_017171281.1  E3 ubiquitin-protein ligase MYCBP2 isoform X38

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4350 → 4404
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4184 → 4232
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3673 → 3765
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    14. XM_030247599.1 → XP_030103459.1  E3 ubiquitin-protein ligase MYCBP2 isoform X35

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4384 → 4438
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4218 → 4266
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3707 → 3799
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    15. XM_017315788.2 → XP_017171277.1  E3 ubiquitin-protein ligase MYCBP2 isoform X32

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4402 → 4456
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4236 → 4284
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3725 → 3817
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    16. XM_017315787.2 → XP_017171276.1  E3 ubiquitin-protein ligase MYCBP2 isoform X28

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4436 → 4490
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4270 → 4318
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3759 → 3851
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    17. XM_036158382.1 → XP_036014275.1  E3 ubiquitin-protein ligase MYCBP2 isoform X31

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (9) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4410 → 4464
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:4244 → 4292
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3733 → 3825
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1235 → 1385
      PHR; PHR domain
      pfam08239
      Location:2477 → 2539
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    18. XM_011244904.3 → XP_011243206.1  E3 ubiquitin-protein ligase MYCBP2 isoform X27

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4444 → 4498
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4278 → 4326
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3767 → 3859
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    19. XM_011244905.3 → XP_011243207.1  E3 ubiquitin-protein ligase MYCBP2 isoform X29

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4425 → 4479
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4259 → 4307
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3748 → 3840
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    20. XM_017315786.2 → XP_017171275.1  E3 ubiquitin-protein ligase MYCBP2 isoform X24

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4459 → 4513
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4293 → 4341
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3782 → 3874
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    21. XM_011244902.3 → XP_011243204.1  E3 ubiquitin-protein ligase MYCBP2 isoform X20

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4477 → 4531
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4311 → 4359
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3800 → 3892
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    22. XM_030247597.1 → XP_030103457.1  E3 ubiquitin-protein ligase MYCBP2 isoform X10

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4511 → 4565
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4345 → 4393
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3834 → 3926
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    23. XM_011244898.3 → XP_011243200.1  E3 ubiquitin-protein ligase MYCBP2 isoform X9

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4519 → 4573
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4353 → 4401
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3842 → 3934
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    24. XM_011244903.3 → XP_011243205.1  E3 ubiquitin-protein ligase MYCBP2 isoform X25

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4450 → 4504
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4284 → 4332
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3773 → 3865
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    25. XM_017315782.2 → XP_017171271.1  E3 ubiquitin-protein ligase MYCBP2 isoform X18

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4484 → 4538
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4318 → 4366
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3807 → 3899
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    26. XM_017315780.2 → XP_017171269.1  E3 ubiquitin-protein ligase MYCBP2 isoform X17

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4499 → 4553
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4333 → 4381
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3825 → 3917
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    27. XM_011244901.3 → XP_011243203.1  E3 ubiquitin-protein ligase MYCBP2 isoform X15

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4502 → 4556
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4336 → 4384
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3825 → 3917
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    28. XM_011244897.3 → XP_011243199.1  E3 ubiquitin-protein ligase MYCBP2 isoform X8

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4536 → 4590
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4370 → 4418
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3859 → 3951
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    29. XM_011244899.3 → XP_011243201.1  E3 ubiquitin-protein ligase MYCBP2 isoform X11

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4510 → 4564
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4344 → 4392
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3833 → 3925
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    30. XM_017315777.2 → XP_017171266.1  E3 ubiquitin-protein ligase MYCBP2 isoform X6

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4540 → 4594
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4374 → 4422
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3866 → 3958
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    31. XM_011244894.3 → XP_011243196.1  E3 ubiquitin-protein ligase MYCBP2 isoform X2

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4543 → 4597
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4377 → 4425
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3866 → 3958
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    32. XM_006518392.3 → XP_006518455.1  E3 ubiquitin-protein ligase MYCBP2 isoform X4

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4541 → 4595
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4375 → 4423
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3867 → 3959
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    33. XM_011244893.3 → XP_011243195.1  E3 ubiquitin-protein ligase MYCBP2 isoform X1

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (8) summary
      COG5184
      Location:906 → 1026
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4544 → 4598
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:958 → 1006
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1729 → 1884
      PHR; PHR domain
      pfam13540
      Location:683 → 712
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:4378 → 4426
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3867 → 3959
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2394 → 2445
      Filamin; Filamin/ABP280 repeat

    34. XM_017315785.2 → XP_017171274.1  E3 ubiquitin-protein ligase MYCBP2 isoform X23

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (7) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4461 → 4515
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1688 → 1843
      PHR; PHR domain
      cd19799
      Location:4295 → 4343
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3784 → 3876
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2353 → 2404
      Filamin; Filamin/ABP280 repeat

    35. XM_017315791.2 → XP_017171280.1  E3 ubiquitin-protein ligase MYCBP2 isoform X37

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (7) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4364 → 4418
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1691 → 1846
      PHR; PHR domain
      cd19799
      Location:4198 → 4246
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3687 → 3779
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2356 → 2407
      Filamin; Filamin/ABP280 repeat

    36. XM_036158383.1 → XP_036014276.1  E3 ubiquitin-protein ligase MYCBP2 isoform X34

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4387 → 4441
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:4221 → 4269
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3710 → 3802
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1199 → 1349
      PHR; PHR domain
      pfam08239
      Location:2439 → 2501
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:2356 → 2407
      Filamin; Filamin/ABP280 repeat

    37. XM_017315784.2 → XP_017171273.1  E3 ubiquitin-protein ligase MYCBP2 isoform X22

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (7) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4464 → 4518
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1691 → 1846
      PHR; PHR domain
      cd19799
      Location:4298 → 4346
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3787 → 3879
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2356 → 2407
      Filamin; Filamin/ABP280 repeat

    38. XM_017315778.2 → XP_017171267.1  E3 ubiquitin-protein ligase MYCBP2 isoform X14

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (7) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4506 → 4560
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1691 → 1846
      PHR; PHR domain
      cd19799
      Location:4340 → 4388
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3829 → 3921
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2356 → 2407
      Filamin; Filamin/ABP280 repeat

    39. XM_017315790.2 → XP_017171279.1  E3 ubiquitin-protein ligase MYCBP2 isoform X36

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (7) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4366 → 4420
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1693 → 1848
      PHR; PHR domain
      cd19799
      Location:4200 → 4248
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3689 → 3781
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2358 → 2409
      Filamin; Filamin/ABP280 repeat

    40. XM_011244900.3 → XP_011243202.1  E3 ubiquitin-protein ligase MYCBP2 isoform X13

      UniProtKB/Swiss-Prot
      E9PUJ6, Q6PCM8, Q7TPH6
      Conserved Domains (7) summary
      COG5184
      Location:683 → 988
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd16463
      Location:4508 → 4562
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:922 → 970
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1693 → 1848
      PHR; PHR domain
      cd19799
      Location:4342 → 4390
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:3831 → 3923
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:2358 → 2409
      Filamin; Filamin/ABP280 repeat

    41. XM_030247601.1 → XP_030103461.1  E3 ubiquitin-protein ligase MYCBP2 isoform X41

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      cd16463
      Location:3587 → 3641
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      pfam00415
      Location:3 → 51
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:772 → 927
      PHR; PHR domain
      pfam08239
      Location:1520 → 1582
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:39 → 67
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd19799
      Location:3421 → 3469
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2910 → 3002
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      cl27659
      Location:1437 → 1488
      Filamin; Filamin/ABP280 repeat

    42. XM_011244907.3 → XP_011243209.1  E3 ubiquitin-protein ligase MYCBP2 isoform X40

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      cd16463
      Location:3589 → 3643
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:3423 → 3471
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2912 → 3004
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:3 → 51
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:280 → 430
      PHR; PHR domain
      pfam08239
      Location:1522 → 1584
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:39 → 67
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:1439 → 1490
      Filamin; Filamin/ABP280 repeat

    43. XM_036158385.1 → XP_036014278.1  E3 ubiquitin-protein ligase MYCBP2 isoform X40

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      cd16463
      Location:3589 → 3643
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:3423 → 3471
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2912 → 3004
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:3 → 51
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:280 → 430
      PHR; PHR domain
      pfam08239
      Location:1522 → 1584
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:39 → 67
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:1439 → 1490
      Filamin; Filamin/ABP280 repeat

    44. XM_030247600.2 → XP_030103460.1  E3 ubiquitin-protein ligase MYCBP2 isoform X40

      UniProtKB/TrEMBL
      F6SMY7
      Conserved Domains (8) summary
      cd16463
      Location:3589 → 3643
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:3423 → 3471
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2912 → 3004
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam00415
      Location:3 → 51
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:280 → 430
      PHR; PHR domain
      pfam08239
      Location:1522 → 1584
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:39 → 67
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cl27659
      Location:1439 → 1490
      Filamin; Filamin/ABP280 repeat

    45. XM_036158388.1 → XP_036014281.1  E3 ubiquitin-protein ligase MYCBP2 isoform X44

      Conserved Domains (6) summary
      cd16463
      Location:2880 → 2934
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:2714 → 2762
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2203 → 2295
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72 → 229
      PHR; PHR domain
      pfam08239
      Location:821 → 883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738 → 789
      Filamin; Filamin/ABP280 repeat

    46. XM_036158389.1 → XP_036014282.1  E3 ubiquitin-protein ligase MYCBP2 isoform X45

      Conserved Domains (6) summary
      cd16463
      Location:2821 → 2875
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:2655 → 2703
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2144 → 2236
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72 → 229
      PHR; PHR domain
      pfam08239
      Location:821 → 883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738 → 789
      Filamin; Filamin/ABP280 repeat

    47. XM_036158390.1 → XP_036014283.1  E3 ubiquitin-protein ligase MYCBP2 isoform X46

      Conserved Domains (6) summary
      cd16463
      Location:2794 → 2848
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:2628 → 2676
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2117 → 2209
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72 → 229
      PHR; PHR domain
      pfam08239
      Location:821 → 883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738 → 789
      Filamin; Filamin/ABP280 repeat

    48. XM_036158387.1 → XP_036014280.1  E3 ubiquitin-protein ligase MYCBP2 isoform X43

      Conserved Domains (6) summary
      cd16463
      Location:2888 → 2942
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:2722 → 2770
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2211 → 2303
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:72 → 229
      PHR; PHR domain
      pfam08239
      Location:821 → 883
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:738 → 789
      Filamin; Filamin/ABP280 repeat

    49. XM_036158386.1 → XP_036014279.1  E3 ubiquitin-protein ligase MYCBP2 isoform X42

      Conserved Domains (6) summary
      cd16463
      Location:2890 → 2944
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cd19799
      Location:2724 → 2772
      Bbox2_MYCBP2; B-box-type 2 zinc finger found in Myc-binding protein 2 (MYCBP2) and similar proteins
      cl02148
      Location:2213 → 2305
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
      pfam08005
      Location:74 → 231
      PHR; PHR domain
      pfam08239
      Location:823 → 885
      SH3_3; Bacterial SH3 domain
      cl27659
      Location:740 → 791
      Filamin; Filamin/ABP280 repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TPH6.3 GenPept UniProtKB/Swiss-Prot:Q7TPH6

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