Susd5 sushi domain containing 5 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Susd5provided by MGI
Official Full Name: sushi domain containing 5provided by MGI
Primary source: MGI:MGI:2685972
See related: Ensembl:ENSMUSG00000086596 AllianceGenome:MGI:2685972
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1126
Summary: Acts upstream of or within Notch signaling pathway. Orthologous to human SUSD5 (sushi domain containing 5). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in limb E14.5 (RPKM 11.8), cortex adult (RPKM 1.2) and 4 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9 F3; 9 64.23 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (113886422..113927801)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (114057354..114098733)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within Notch signaling pathway	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: sushi domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101510.1 → NP_001094980.1 sushi domain-containing protein 5 precursor

See identical proteins and their annotated locations for NP_001094980.1

Status: VALIDATED

Source sequence(s)

AK132299, BB400929, BY339287, BY718562

Consensus CDS

CCDS52949.1

UniProtKB/TrEMBL

G3UW60

Related

ENSMUSP00000128826.2, ENSMUST00000135338.3

Conserved Domains (1) summary

cl02612
Location:35 → 129

Link_Domain; The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor ...