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    Med9 mediator complex subunit 9 [ Mus musculus (house mouse) ]

    Gene ID: 192191, updated on 2-Nov-2024

    Summary

    Official Symbol
    Med9provided by MGI
    Official Full Name
    mediator complex subunit 9provided by MGI
    Primary source
    MGI:MGI:2183151
    See related
    Ensembl:ENSMUSG00000061650 AllianceGenome:MGI:2183151
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Med25
    Summary
    Predicted to enable transcription coregulator activity. Part of mediator complex. Orthologous to human MED9 (mediator complex subunit 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 21.0), adrenal adult (RPKM 15.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Med9 in Genome Data Viewer
    Location:
    11 B1.3; 11 37.81 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59839040..59854132)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59948214..59963306)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51900 Neighboring gene mediator complex subunit 9, opposite strand Neighboring gene RAS, dexamethasone-induced 1 Neighboring gene phosphatidylethanolamine N-methyltransferase Neighboring gene predicted gene, 53709 Neighboring gene predicted gene, 38498

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ10193, MGC30366

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of core mediator complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 9
    Names
    mediator of RNA polymerase II transcription, subunit 9 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138675.3NP_619616.2  mediator of RNA polymerase II transcription subunit 9

      See identical proteins and their annotated locations for NP_619616.2

      Status: VALIDATED

      Source sequence(s)
      AL603710, BY295874
      Consensus CDS
      CCDS24780.1
      UniProtKB/Swiss-Prot
      Q8BHQ8, Q8R5H4, Q8VCS6
      Related
      ENSMUSP00000080641.7, ENSMUST00000081980.7
      Conserved Domains (1) summary
      pfam07544
      Location:60132
      Med9; RNA polymerase II transcription mediator complex subunit 9

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      59839040..59854132
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)