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    Zfp825 zinc finger protein 825 [ Mus musculus (house mouse) ]

    Gene ID: 235956, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Zfp825provided by MGI
    Official Full Name
    zinc finger protein 825provided by MGI
    Primary source
    MGI:MGI:2385315
    See related
    Ensembl:ENSMUSG00000069208 AllianceGenome:MGI:2385315
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system and genitourinary system. [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 1.2), CNS E11.5 (RPKM 1.1) and 24 other tissues See more
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    Genomic context

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    See Zfp825 in Genome Data Viewer
    Location:
    13 C1; 13 40.33 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74626497..74642132, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (74478378..74494012, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35009 Neighboring gene predicted gene, 41004 Neighboring gene RIKEN cDNA E430024I08 gene Neighboring gene STARR-seq mESC enhancer starr_35011 Neighboring gene predicted gene, 57595 Neighboring gene STARR-positive B cell enhancer ABC_E4079 Neighboring gene STARR-positive B cell enhancer ABC_E9401 Neighboring gene STARR-seq mESC enhancer starr_35015 Neighboring gene upstream binding transcription factor, RNA polymerase I pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7252 Neighboring gene stomatin (Epb7.2)-like 2 pseudogene Neighboring gene predicted gene, 57808 Neighboring gene predicted gene, 57809

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Ulmke PA, et al. Stem Cell Reports, 2021 Apr 13. PMID 33798452, Free PMC Article
    2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Clone Names

    • MGC18736

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 124

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374752.1 → NP_001361681.1  zinc finger protein 124 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT009718
      Consensus CDS
      CCDS88485.1
      UniProtKB/TrEMBL
      A0A1Y7VK00
      Conserved Domains (3) summary
      COG5048
      Location:119 → 271
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:207 → 227
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:22 → 62
      KRAB; KRAB box

    2. NM_001377115.1 → NP_001364044.1  zinc finger protein 124 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT009718
      UniProtKB/TrEMBL
      A0A1Y7VK00
      Related
      ENSMUSP00000152719.2, ENSMUST00000221173.2
      Conserved Domains (3) summary
      COG5048
      Location:119 → 271
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:207 → 227
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:22 → 62
      KRAB; KRAB box

    3. NM_146231.2 → NP_666343.1  zinc finger protein 124 isoform 2

      See identical proteins and their annotated locations for NP_666343.1

      Status: VALIDATED

      Source sequence(s)
      CT009718
      Consensus CDS
      CCDS79212.1
      UniProtKB/TrEMBL
      Q91VL6
      Related
      ENSMUSP00000144128.2, ENSMUST00000202645.4
      Conserved Domains (3) summary
      COG5048
      Location:101 → 253
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:189 → 209
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      74626497..74642132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247254.2 → XP_030103114.1  zinc finger protein 124 isoform X1

      Related
      ENSMUSP00000073973.7, ENSMUST00000074369.7
      Conserved Domains (2) summary
      COG5048
      Location:69 → 221
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:157 → 177
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_036158036.1 → XP_036013929.1  zinc finger protein 124 isoform X1

      Conserved Domains (2) summary
      COG5048
      Location:69 → 221
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:157 → 177
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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