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    C16orf95 chromosome 16 open reading frame 95 [ Homo sapiens (human) ]

    Gene ID: 100506581, updated on 17-Sep-2024

    Summary

    Official Symbol
    C16orf95provided by HGNC
    Official Full Name
    chromosome 16 open reading frame 95provided by HGNC
    Primary source
    HGNC:HGNC:40033
    See related
    Ensembl:ENSG00000260456 AllianceGenome:HGNC:40033
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in testis (RPKM 33.1) and bone marrow (RPKM 1.2) See more
    Orthologs
    NEW
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    Genomic context

    See C16orf95 in Genome Data Viewer
    Location:
    16q24.2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (87302814..87317392, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (93373698..93388274, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (87336420..87350998, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928682 Neighboring gene ribosomal protein L39 pseudogene 30 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87312649-87313154 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87329362-87330350 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87330351-87331337 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87339626-87340209 Neighboring gene small nucleolar RNA U13 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87348819-87349319 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11320 Neighboring gene C16orf95 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87364853-87365354 Neighboring gene F-box protein 31 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87379751-87380306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87380307-87380861 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87386425-87386966 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:87399801-87400302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87403399-87404245 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7833 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:87417185-87417838 Neighboring gene uncharacterized LOC124903747 Neighboring gene tRNA-Met (anticodon CAT) 6-1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein C16orf95

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195124.3NP_001182053.1  uncharacterized protein C16orf95 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC010531
      Consensus CDS
      CCDS58491.1
      UniProtKB/TrEMBL
      H3BNZ7
      Related
      ENSP00000455079.2, ENST00000567970.2
      Conserved Domains (1) summary
      pfam15132
      Location:76239
      DUF4568; Domain of unknown function (DUF4568)
    2. NM_001195125.3NP_001182054.1  uncharacterized protein C16orf95 isoform 2

      See identical proteins and their annotated locations for NP_001182054.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two alternate exons that result in a frameshift in the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC010531, BC015536, BU839368
      Consensus CDS
      CCDS54049.1
      UniProtKB/Swiss-Prot
      Q9H693
      Related
      ENSP00000253461.4, ENST00000253461.8
      Conserved Domains (1) summary
      pfam15132
      Location:76110
      DUF4568; Domain of unknown function (DUF4568)
    3. NM_001256917.2NP_001243846.1  uncharacterized protein C16orf95 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate 5' exon and an alternate start codon, and lacks two exons that result in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (3) shares similarity in the central region but has distinct N- and C-termini and is overall shorter, compared to isoform 1.
      Source sequence(s)
      AB371437, AC010531, BC015536, BI460222, BU839368, DA871621
      Consensus CDS
      CCDS73921.1
      UniProtKB/TrEMBL
      A0A087X224
      Related
      ENSP00000484646.1, ENST00000618367.4
      Conserved Domains (1) summary
      pfam15132
      Location:5495
      DUF4568; Domain of unknown function (DUF4568)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      87302814..87317392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      93373698..93388274 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)