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    nceh1b.1 neutral cholesterol ester hydrolase 1b, tandem duplicate 1 [ Danio rerio (zebrafish) ]

    Gene ID: 777713, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nceh1b.1provided by ZNC
    Official Full Name
    neutral cholesterol ester hydrolase 1b, tandem duplicate 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061110-43
    See related
    Ensembl:ENSDARG00000062087 AllianceGenome:ZFIN:ZDB-GENE-061110-43
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nceh1b; zgc:153038
    Summary
    Predicted to enable serine hydrolase activity. Predicted to act upstream of or within lipid catabolic process. Predicted to be located in endoplasmic reticulum and plasma membrane. Orthologous to human NCEH1 (neutral cholesterol ester hydrolase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See nceh1b.1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (26895821..26902694)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (26816662..26823535)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene fibronectin type III domain containing 3Bb Neighboring gene neutral cholesterol ester hydrolase 1 Neighboring gene TNF superfamily member 10 Neighboring gene MSL complex subunit 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Structures, evolutionary relationships and expression profiles of the tumour necrosis factor superfamily and their receptors in black rockfish (Sebastes schlegelii). Cao M, et al. Dev Comp Immunol, 2022 Jul. PMID 35364135
    2. Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis. Biswas G, et al. Mar Genomics, 2015 Aug. PMID 25792259
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acetylalkylglycerol acetylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC777713
    NP_001071229.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077761.1 → NP_001071229.1  uncharacterized protein LOC777713

      See identical proteins and their annotated locations for NP_001071229.1

      Status: PREDICTED

      Source sequence(s)
      BC125851
      UniProtKB/TrEMBL
      A0JME8
      Related
      ENSDARP00000083784.4, ENSDART00000089351.5
      Conserved Domains (2) summary
      COG0657
      Location:88 → 408
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam07859
      Location:108 → 382
      Abhydrolase_3; alpha/beta hydrolase fold

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      26895821..26902694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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