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    rab12 RAB12, member RAS oncogene family [ Danio rerio (zebrafish) ]

    Gene ID: 553657, updated on 9-Dec-2024

    Summary

    Official Symbol
    rab12provided by ZNC
    Official Full Name
    RAB12, member RAS oncogene familyprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-555
    See related
    Ensembl:ENSDARG00000089428 AllianceGenome:ZFIN:ZDB-GENE-050522-555
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:111945
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in endocytic recycling and exocytosis. Predicted to act upstream of or within Rab protein signal transduction. Predicted to be active in cytoplasmic vesicle and plasma membrane. Is expressed in hindbrain; neural crest; and pharyngeal arch. Orthologous to human RAB12 (RAB12, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See rab12 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (54387710..54419031)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (54663063..54694384)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene cathepsin Z Neighboring gene piezo type mechanosensitive ion channel component 2 Neighboring gene uncharacterized LOC101882917 Neighboring gene N-ethylmaleimide-sensitive factor attachment protein, gamma b Neighboring gene microtubule crosslinking factor 1 Neighboring gene acyl-CoA synthetase short chain family member 2 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC111945

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within Rab protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synaptic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in trans-Golgi network transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020630.1NP_001018466.1  ras-related protein Rab-12

      See identical proteins and their annotated locations for NP_001018466.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095608
      UniProtKB/TrEMBL
      B2GS97, F6P1S2, Q502Q0
      Related
      ENSDARP00000110018.1, ENSDART00000127124.2
      Conserved Domains (2) summary
      smart00175
      Location:36200
      RAB; Rab subfamily of small GTPases
      cd04120
      Location:36235
      Rab12; Rab GTPase family 12 (Rab12)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      54387710..54419031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)