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    SMAD1 SMAD family member 1 [ Mirounga leonina (Southern elephant seal) ]

    Gene ID: 118022276, updated on 20-Mar-2024

    Summary

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    Gene symbol
    SMAD1
    Gene description
    SMAD family member 1
    Locus tag
    GH733_012015
    See related
    EnsemblRapid:ENSMLOG00005004065
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mirounga leonina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Mirounga
    Orthologs
    human mouse all
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    Genomic context

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    See SMAD1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    100 current KU_Mleo_1.0 (GCF_011800145.1) Unplaced Scaffold NW_023270454.1 (39543561..39649352, complement)

    NW_023270454.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C4orf51 homolog Neighboring gene metabolism of cobalamin associated A Neighboring gene translation initiation factor IF-2-like Neighboring gene myeloid leukemia factor 1-like Neighboring gene U4 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023270454 Unplaced Scaffold Reference KU_Mleo_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mirounga leonina Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KU_Mleo_1.0 Primary Assembly

    Genomic

    1. NW_023270454.1 Reference KU_Mleo_1.0 Primary Assembly

      Range
      39543561..39649352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035022975.1 → XP_034878866.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    2. XM_035022974.1 → XP_034878865.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    3. XM_035022983.1 → XP_034878874.1  mothers against decapentaplegic homolog 1 isoform X2

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cl00056
      Location:265 → 419
      MH2; C-terminal Mad Homology 2 (MH2) domain

    4. XM_035022973.1 → XP_034878864.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    5. XM_035022969.1 → XP_034878860.1  mothers against decapentaplegic homolog 1 isoform X1

      Related
      ENSMLOP00005005531.1, ENSMLOT00005006390.1
      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    6. XM_035022972.1 → XP_034878863.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    7. XM_035022970.1 → XP_034878861.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    8. XM_035022976.1 → XP_034878867.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    9. XM_035022978.1 → XP_034878869.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    10. XM_035022982.1 → XP_034878873.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    11. XM_035022981.1 → XP_034878872.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    12. XM_035022980.1 → XP_034878871.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    13. XM_035022979.1 → XP_034878870.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    14. XM_035022971.1 → XP_034878862.1  mothers against decapentaplegic homolog 1 isoform X1

      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
    Nucleotide Protein
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