HNF1A-AS1 HNF1A antisense RNA 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: HNF1A-AS1provided by HGNC
Official Full Name: HNF1A antisense RNA 1provided by HGNC
Primary source: HGNC:HGNC:26785
See related: Ensembl:ENSG00000241388 AllianceGenome:HGNC:26785
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: HAS1; HASTER; C12orf27; NCRNA00262
Summary: Biomarker of colon cancer and stomach cancer. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 12q24.31

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	12	NC_000012.12 (120969838..120972292, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	12	NC_060936.1 (120959530..120961984, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	12	NC_000012.11 (121407641..121410095, complement)

Chromosome 12 - NC_000012.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CMYC-initiated HNF1A-AS1 overexpression maintains the stemness of gastric cancer cells.
Title: CMYC-initiated HNF1A-AS1 overexpression maintains the stemness of gastric cancer cells.
The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
Title: The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer.
Title: The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer.
HNF1A-AS1: A Tumor-associated Long Non-coding RNA.
Title: HNF1A-AS1: A Tumor-associated Long Non-coding RNA.
sh-HNF1A-AS1 reduces the epithelial-mesenchymal transition and stemness of esophageal cancer cells.
Title: sh-HNF1A-AS1 reduces the epithelial-mesenchymal transition and stemness of esophageal cancer cells.
Differential expression of HNF1A and HNF1A-AS1 in colon cancer cells.
Title: Differential expression of HNF1A and HNF1A-AS1 in colon cancer cells.
The HNF1A-AS1/miR-92a-3p axis affects the radiosensitivity of non-small cell lung cancer by competitively regulating the JNK pathway.
Title: The HNF1A-AS1/miR-92a-3p axis affects the radiosensitivity of non-small cell lung cancer by competitively regulating the JNK pathway.
Silencing long non-coding RNA HNF1A-AS1 inhibits growth and resistance to TAM of breast cancer cells via the microRNA-363/SERTAD3 axis.
Title: Silencing long non-coding RNA HNF1A-AS1 inhibits growth and resistance to TAM of breast cancer cells via the microRNA-363/SERTAD3 axis.
Deletion of HNF1A-AS1 Suppresses the Malignant Phenotypes of Breast Cancer Cells In Vitro and In Vivo Through Targeting miRNA-20a-5p/TRIM32 Axis.
Title: Deletion of HNF1A-AS1 Suppresses the Malignant Phenotypes of Breast Cancer Cells In Vitro and In Vivo Through Targeting miRNA-20a-5p/TRIM32 Axis.
Long noncoding RNA HNF1A-AS1 regulates proliferation and apoptosis of glioma through activation of the JNK signaling pathway via miR-363-3p/MAP2K4.
Title: Long noncoding RNA HNF1A-AS1 regulates proliferation and apoptosis of glioma through activation of the JNK signaling pathway via miR-363-3p/MAP2K4.

Submit: New GeneRIF Correction See all GeneRIFs (31)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genetic Loci Associated with Circulating Levels of Very Long-Chain Saturated Fatty Acids. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. EBI GWAS Catalog EBI GWAS CatalogPubMed
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See studies and variants in dbVar

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

GDB:434012 (e-PCR)
- UniSTS:157204

D11S2560 (e-PCR)
- UniSTS:37928

D8S2279 (e-PCR)
- UniSTS:473907

D15S1477 (e-PCR)
- UniSTS:474482

L18441 (e-PCR)
- UniSTS:71348

Other Names

HNF1A antisense RNA 1 (non-protein coding)
HNF1A stabilizer transcripts

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.