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    LINC02953 long intergenic non-protein coding RNA 2953 [ Homo sapiens (human) ]

    Gene ID: 102724265, updated on 17-Jun-2024

    Summary

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    Official Symbol
    LINC02953provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2953provided by HGNC
    Primary source
    HGNC:HGNC:55970
    See related
    Ensembl:ENSG00000255980
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    all
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    Genomic context

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    See LINC02953 in Genome Data Viewer
    Location:
    11q13.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (69425655..69429624)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (69442793..69446762)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (69240423..69244392)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69078345-69078844 Neighboring gene interferon induced transmembrane protein 9 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69088091-69088958 Neighboring gene uncharacterized LOC105369370 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5158 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69153613-69154114 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69154115-69154614 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69157262-69158194 Neighboring gene MPRA-validated peak1324 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69214023-69214785 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69215486-69215986 Neighboring gene CRISPRi-validated cis-regulatory element chr11.3768 Neighboring gene CRISPRi-validated cis-regulatory element chr11.3769 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69234157-69234732 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69235307-69235881 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69249331-69250160 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69251823-69252654 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69253485-69254316 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5159 Neighboring gene long intergenic non-protein coding RNA 2952 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3693 Neighboring gene uncharacterized LOC124902703 Neighboring gene GATA motif-containing MPRA enhancer 291 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:69270026-69270770 Neighboring gene NANOG hESC enhancer GRCh37_chr11:69276040-69276608 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69278453-69279186 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69289663-69290348 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:69290349-69291033 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:69291034-69291718 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69291719-69292403 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:69295265-69296231 Neighboring gene long intergenic non-protein coding RNA 2747

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Purdue MP, et al. Nat Genet, 2011 Jan. PMID 21131975, Free PMC Article
    2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Homology

    Clone Names

    • AP000439.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_172877.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AP000439
      Related
      ENST00000545202.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      69425655..69429624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      69442793..69446762
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001319657.2: Suppressed sequence

      Description
      NM_001319657.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials