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    LOC102352257 prostaglandin G/H synthase 2 [ Latimeria chalumnae (coelacanth) ]

    Gene ID: 102352257, updated on 30-Apr-2024

    Summary

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    Gene symbol
    LOC102352257
    Gene description
    prostaglandin G/H synthase 2
    See related
    Ensembl:ENSLACG00000008168
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Latimeria chalumnae
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
    Also known as
    PTGS2
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    Genomic context

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    See LOC102352257 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 6 NC_088144.1 (46632085..46643163, complement)
    101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005820995.1 (313280..336029)

    Chromosome 6 - NC_088144.1Genomic Context describing neighboring genes Neighboring gene phosducin Neighboring gene odr-4 GPCR localization factor homolog Neighboring gene uncharacterized LOC102357157 Neighboring gene cytosolic phospholipase A2 Neighboring gene 5S ribosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables prostaglandin-endoperoxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cyclooxygenase pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prostaglandin G/H synthase 2
    Names
    prostaglandin-endoperoxide synthase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fLatCha1.pri

    Genomic

    1. NC_088144.1 Reference fLatCha1.pri

      Range
      46632085..46643163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006009250.3 → XP_006009312.1  prostaglandin G/H synthase 2 isoform X2

      UniProtKB/TrEMBL
      M3XGW9
      Related
      ENSLACP00000021975.1
      Conserved Domains (2) summary
      cd09816
      Location:72 → 560
      prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins
      cd00054
      Location:16 → 52
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

    2. XM_006009249.3 → XP_006009311.1  prostaglandin G/H synthase 2 isoform X1

      UniProtKB/TrEMBL
      H3AHY9
      Related
      ENSLACP00000009260.1
      Conserved Domains (2) summary
      cd09816
      Location:90 → 578
      prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins
      cd00054
      Location:34 → 70
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    Nucleotide Protein
    Heading Accession and Version

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