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    mpc2b mitochondrial pyruvate carrier 2b [ Danio rerio (zebrafish) ]

    Gene ID: 321611, updated on 2-Nov-2024

    Summary

    Official Symbol
    mpc2bprovided by ZNC
    Official Full Name
    mitochondrial pyruvate carrier 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-330
    See related
    Ensembl:ENSDARG00000024478 AllianceGenome:ZFIN:ZDB-GENE-030131-330
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mpc2; brp44; zgc:56391; zgc:86614; wu:fb22b02; wu:fb22g07
    Summary
    Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; optic tectum; and pectoral fin. Orthologous to human MPC2 (mitochondrial pyruvate carrier 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See mpc2b in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (34222027..34227317)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (34412842..34418132)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 161b Neighboring gene ddb1 and cul4 associated factor 6 Neighboring gene neurexophilin and PC-esterase domain family, member 3 Neighboring gene malic enzyme 3, NADP(+)-dependent, mitochondrial

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables pyruvate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial pyruvate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mitochondrial pyruvate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitochondrial pyruvate carrier 2b
    Names
    brain protein 44
    mitochondrial pyruvate carrier 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212592.1NP_997757.1  mitochondrial pyruvate carrier 2b

      See identical proteins and their annotated locations for NP_997757.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049015
      UniProtKB/TrEMBL
      Q7ZUJ3
      Related
      ENSDARP00000031014.7, ENSDART00000028617.8
      Conserved Domains (1) summary
      pfam03650
      Location:24125
      MPC; uncharacterized protein family (UPF0041)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      34222027..34227317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)