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    Cimap2 ciliary microtubule associated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 242602, updated on 6-Oct-2024

    Summary

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    Official Symbol
    Cimap2provided by MGI
    Official Full Name
    ciliary microtubule associated protein 2provided by MGI
    Primary source
    MGI:MGI:2681853
    See related
    Ensembl:ENSMUSG00000054362 AllianceGenome:MGI:2681853
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lexm
    Summary
    Enables mitochondrial ribosome binding activity. Acts upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Located in mitochondrion. Orthologous to human LEXM (lymphocyte expansion molecule). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 13.2) See more
    Orthologs
    human all
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    Genomic context

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    See Cimap2 in Genome Data Viewer
    Location:
    4 C7; 4 49.67 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (106448105..106474594, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (106590908..106617397, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2700068H02 gene Neighboring gene STARR-positive B cell enhancer ABC_E10243 Neighboring gene 24-dehydrocholesterol reductase Neighboring gene STARR-seq mESC enhancer starr_10995 Neighboring gene STARR-seq mESC enhancer starr_10996 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:106287642-106287893 Neighboring gene STARR-positive B cell enhancer ABC_E10244 Neighboring gene tetratricopeptide repeat domain 22 Neighboring gene STARR-positive B cell enhancer ABC_E2700 Neighboring gene prolyl-tRNA synthetase (mitochondrial)(putative)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC58608

    General protein information

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    Preferred Names
    ciliary microtubule-associated protein 2
    Names
    lymphocyte expansion molecule

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183182.4 → NP_899005.2  ciliary microtubule-associated protein 2

      See identical proteins and their annotated locations for NP_899005.2

      Status: VALIDATED

      Source sequence(s)
      AL929585
      Consensus CDS
      CCDS51252.1
      UniProtKB/Swiss-Prot
      A2AVQ4, A2AVQ5, Q7TPM4
      UniProtKB/TrEMBL
      A0A0F6T326
      Related
      ENSMUSP00000102400.2, ENSMUST00000106788.2

    RNA

    1. NR_149753.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL929585

    2. NR_189597.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL929585

    3. NR_189598.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL929585

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      106448105..106474594 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011240528.3 → XP_011238830.1  ciliary microtubule-associated protein 2 isoform X1

    2. XM_006503086.5 → XP_006503149.1  ciliary microtubule-associated protein 2 isoform X2

    3. XM_030253564.1 → XP_030109424.1  ciliary microtubule-associated protein 2 isoform X4

    4. XM_030253565.2 → XP_030109425.1  ciliary microtubule-associated protein 2 isoform X4

    5. XM_011240529.3 → XP_011238831.1  ciliary microtubule-associated protein 2 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2AVQ5.1 GenPept UniProtKB/Swiss-Prot:A2AVQ5

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