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    NP nucleoprotein [ Influenza A virus (A/Korea/426/1968(H2N2)) ]

    Gene ID: 3655111, updated on 18-Aug-2023

    Summary

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    Gene symbol
    NP
    Gene description
    nucleoprotein
    Locus tag
    FLUAVH2N2_s5p1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Influenza A virus (A/Korea/426/1968(H2N2)) (strain: A/Korea/426/1968, serotype: H2N2, nat-host: Homo sapiens)
    Lineage
    Viruses; ssRNA viruses; ssRNA negative-strand viruses; Orthomyxoviridae; Influenzavirus A
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    Genomic context

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    Location:
    segment: 5
    Sequence:
    NC_007381.1 (1..1497)

    NC_007381.1Genomic Context describing neighboring genes

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007381.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity. Boon AC, et al. J Virol, 2006 Jun. PMID 16731941, Free PMC Article
    2. Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells. Danzy S, et al. J Virol, 2014 Nov. PMID 25210184, Free PMC Article
    3. Genetic analysis of human H2N2 and early H3N2 influenza viruses, 1957-1972: evidence for genetic divergence and multiple reassortment events. Lindstrom SE, et al. Virology, 2004 Oct 10. PMID 15380362

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results show that mutations in NP arise during adaptation of an avian influenza A virus to human respiratory cells and that the mutations confer efficient growth.
      Title: Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells.
    2. the high functional avidity of NP(418-426)-specific CTL was responsible for the diversification of this influenza A virus CTL epitope
      Title: The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    nucleoprotein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007381.1 Reference assembly

      Range
      1..1497
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_308871.1 nucleoprotein [Influenza A virus (A/Korea/426/1968(H2N2))]

      See identical proteins and their annotated locations for YP_308871.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0A7E4V0, A4GCB3, A4GCC4, A4GCD5, A5GX99, B2VMQ7, C0RSJ4, E6XTQ5, G0KTY4, K4P0Y6, K4P3A9, K4PEC9, Q6XTP9, Q6XTQ4
      Conserved Domains (1) summary
      pfam00506
      Location:1 → 498
      Flu_NP; Influenza virus nucleoprotein
    Nucleotide Protein
    Heading Accession and Version

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