TNF tumor necrosis factor [Callithrix jacchus (white-tufted-ear marmoset)] - Gene

Summary

Gene symbol: TNF
Gene description: tumor necrosis factor
See related: Ensembl:ENSCJAG00000003109
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Callithrix jacchus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Also known as: TNFA; TNF-a; TNFSF2; TNF-alpha
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_03	current	mCalJa1.2.pat.X (GCF_011100555.1)	4	NC_071445.1 (35188254..35190155)
105	previous assembly	Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1)	4	NC_048386.1 (35786290..35788191)

Chromosome 4 - NC_071445.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The results of this meta-analysis suggested that the polymorphism of TNF-alpha-308 G>A participates in modifying the susceptibility to ulcerative colitis and Crohn's disease in Europeans and Asians
Title: Relationship between the polymorphism of tumor necrosis factor-α-308 G>A and susceptibility to inflammatory bowel diseases and colorectal cancer: a meta-analysis.

Submit: New GeneRIF Correction

General gene information

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Markers

Tnf (e-PCR), detects polymorphism
- UniSTS:144649

RH17367 (e-PCR)
- UniSTS:56874

PMC108024P2 (e-PCR)
- UniSTS:270131

GDB:624603 (e-PCR)
- UniSTS:158353

GDB:624619 (e-PCR)
- UniSTS:158354

PMC165077P1 (e-PCR)
- UniSTS:271531

PMC165077P2 (e-PCR)
- UniSTS:271532

PMC97302P1 (e-PCR)
- UniSTS:273646

TNF (e-PCR), detects polymorphism
- UniSTS:264951

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CD40 receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of NF-kappaB transcription factor activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tumor necrosis factor-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tumor necrosis factor

Names: TNF alpha; cachectin; tumor necrosis factor ligand superfamily member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.