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    TLR3 toll like receptor 3 [ Strigops habroptila (Kakapo) ]

    Gene ID: 115610386, updated on 3-Aug-2024

    Summary

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    Gene symbol
    TLR3
    Gene description
    toll like receptor 3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strigops habroptila
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Psittaciformes; Psittacidae; Strigops
    Orthologs
    human mouse all
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    Genomic context

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    See TLR3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    101 current bStrHab1.2.pri (GCF_004027225.2) 7 NC_044283.2 (33401160..33412216, complement)
    100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 7 NC_044283.1 (33185669..33196725, complement)

    Chromosome 7 - NC_044283.2Genomic Context describing neighboring genes Neighboring gene cytochrome P450 4V2 Neighboring gene family with sequence similarity 149 member A Neighboring gene sorbin and SH3 domain containing 2 Neighboring gene PDZ and LIM domain 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    toll-like receptor 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bStrHab1.2.pri

    Genomic

    1. NC_044283.2 Reference bStrHab1.2.pri

      Range
      33401160..33412216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030491844.1 → XP_030347704.1  toll-like receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A672UH12
      Conserved Domains (7) summary
      PRK15370
      Location:518 → 674
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      smart00082
      Location:662 → 714
      LRRCT; Leucine rich repeat C-terminal domain
      smart00255
      Location:773 → 915
      TIR; Toll - interleukin 1 - resistance
      sd00033
      Location:374 → 397
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:449 → 502
      LRR_8; Leucine rich repeat
      pfam17968
      Location:715 → 747
      Tlr3_TMD; Toll-like receptor 3 trans-membrane domain
      NF033189
      Location:79 → 459
      internalin_A; class 1 internalin InlA

    2. XM_032920052.1 → XP_032775943.1  toll-like receptor 3 isoform X2

      Conserved Domains (6) summary
      smart00082
      Location:518 → 570
      LRRCT; Leucine rich repeat C-terminal domain
      smart00255
      Location:629 → 771
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:124 → 480
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:230 → 253
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:31 → 92
      LRR_8; Leucine rich repeat
      pfam17968
      Location:571 → 603
      Tlr3_TMD; Toll-like receptor 3 trans-membrane domain

    3. XM_030491845.1 → XP_030347705.1  toll-like receptor 3 isoform X2

      Conserved Domains (6) summary
      smart00082
      Location:518 → 570
      LRRCT; Leucine rich repeat C-terminal domain
      smart00255
      Location:629 → 771
      TIR; Toll - interleukin 1 - resistance
      PLN00113
      Location:124 → 480
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:230 → 253
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:31 → 92
      LRR_8; Leucine rich repeat
      pfam17968
      Location:571 → 603
      Tlr3_TMD; Toll-like receptor 3 trans-membrane domain
    Nucleotide Protein
    Heading Accession and Version

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