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    raraa retinoic acid receptor, alpha a [ Takifugu rubripes (torafugu) ]

    Gene ID: 445948, updated on 5-Mar-2024

    Summary

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    Gene symbol
    raraa
    Gene description
    retinoic acid receptor, alpha a
    See related
    Ensembl:ENSTRUG00000016415
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Takifugu rubripes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu
    Also known as
    rara; nr1b1
    Orthologs
    human zebrafish all
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    Genomic context

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    See raraa in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current fTakRub1.2 (GCF_901000725.2) 1 NC_042285.1 (11161788..11258008, complement)
    101 previous assembly FUGU5 (GCF_000180615.1) 1 NC_018890.1 (7465917..7495126, complement)

    Chromosome 1 - NC_042285.1Genomic Context describing neighboring genes Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene marker of proliferation Ki-67 Neighboring gene uncharacterized LOC115246550 Neighboring gene uncharacterized LOC115246552 Neighboring gene gap junction protein delta 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterisation of the retinoic acid receptor-alpha gene in the Japanese pufferfish, F. rubripes. Wentworth JM, et al. Gene, 1999 Aug 20. PMID 10452951
    2. Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors. Waxman JS, et al. Dev Dyn, 2007 Feb. PMID 17195188
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear glucocorticoid receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to corticotropin-releasing hormone stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in retinoic acid receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    retinoic acid receptor alpha
    Names
    RAR-alpha
    nuclear receptor subfamily 1 group B member 1
    retinoic acid receptor alpha-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032753.1 → NP_001027925.1  retinoic acid receptor alpha

      See identical proteins and their annotated locations for NP_001027925.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ012379
      UniProtKB/TrEMBL
      A0A674NQ35
      Related
      ENSTRUP00000041965.3, ENSTRUT00000042109.3
      Conserved Domains (2) summary
      cd06937
      Location:186 → 415
      NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
      cd06964
      Location:81 → 165
      NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers

    RefSeqs of Annotated Genomes: Takifugu rubripes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fTakRub1.2 Primary Assembly

    Genomic

    1. NC_042285.1 Reference fTakRub1.2 Primary Assembly

      Range
      11161788..11258008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029826335.1 → XP_029682195.1  retinoic acid receptor alpha isoform X1

      UniProtKB/Swiss-Prot
      Q9W5Z3, Q9W5Z4
      UniProtKB/TrEMBL
      A0A674NQ35
      Related
      ENSTRUP00000041963.2, ENSTRUT00000042107.3
      Conserved Domains (2) summary
      cd06937
      Location:179 → 408
      NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
      cd06964
      Location:74 → 158
      NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W5Z3.1 GenPept UniProtKB/Swiss-Prot:Q9W5Z3

    Gene LinkOut

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