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    GUSBP11 GUSB pseudogene 11 [ Homo sapiens (human) ]

    Gene ID: 91316, updated on 2-Nov-2024

    Summary

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    Official Symbol
    GUSBP11provided by HGNC
    Official Full Name
    GUSB pseudogene 11provided by HGNC
    Primary source
    HGNC:HGNC:42325
    See related
    Ensembl:ENSG00000228315 AllianceGenome:HGNC:42325
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This transcribed pseudogene is similar to two functional genes. The 5' portion of the pseudogene is related to glucuronidase, beta, and the 3' portion is related to immunoglobulin lambda-like polypeptide 1. [provided by RefSeq, Jul 2011]
    Expression
    Ubiquitous expression in bone marrow (RPKM 14.2), spleen (RPKM 9.8) and 25 other tissues See more
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    Genomic context

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    See GUSBP11 in Genome Data Viewer
    Location:
    22q11.23
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (23638487..23717423, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (24085633..24164623, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (23980674..24059610, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene aspartate rich 1 Neighboring gene uncharacterized LOC124905089 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:23975547-23975684 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:23991555-23992054 Neighboring gene argininosuccinate lyase pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24016106-24016710 Neighboring gene Sharpr-MPRA regulatory region 3793 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:24037607-24038107 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18756 Neighboring gene ral guanine nucleotide dissociation stimulator like 4 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24059101-24059740 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:24059741-24060380 Neighboring gene uncharacterized LOC124905088 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24087516-24088016 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24088017-24088517 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:24093057-24093732 Neighboring gene zinc finger protein 70

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Long Noncoding RNA GUSBP11 Knockdown Alleviates Nasopharyngeal Carcinoma via Regulating miR-1226-3p/TM9SF4 Axis. Zhang X, et al. Cancer Biother Radiopharm, 2024 Mar. PMID 35675666
    2. Composite exon structure of an unusual Ig lambda-like gene located at human 22q11 position. Schiff C, et al. Mamm Genome, 1996 Aug. PMID 8678981
    3. Isolation of early immunoglobulin lambda-like gene transcripts in human fetal liver. Schiff C, et al. Eur J Immunol, 1989 Oct. PMID 2511029
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • glucuronidase, beta pseudogene 11
    • glucuronidase, beta/immunoglobulin lambda-like polypeptide 1 pseudogene

    Clone Names

    • FLJ52668

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024448.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK056875, AK300413, BC050388, BX538181, DC322250, X52204
      Related
      ENST00000445682.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      23638487..23717423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      24085633..24164623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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