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    FGA fibrinogen alpha chain [ Microcebus murinus (gray mouse lemur) ]

    Gene ID: 105881780, updated on 13-Mar-2024

    Summary

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    Gene symbol
    FGA
    Gene description
    fibrinogen alpha chain
    See related
    Ensembl:ENSMICG00000003234
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcebus murinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
    Orthologs
    human mouse all
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    Genomic context

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    See FGA in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    101 current Mmur_3.0 (GCF_000165445.2) 14 NC_033673.1 (49667596..49681583)
    100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012197797.1 (3377177..3391633)

    Chromosome 14 - NC_033673.1Genomic Context describing neighboring genes Neighboring gene Golgi apparatus membrane protein TVP23 homolog B pseudogene Neighboring gene fibrinogen gamma chain Neighboring gene fibrinogen beta chain Neighboring gene pleiotropic regulator 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in blood coagulation, common pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fibrinolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of endothelial cell apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in platelet activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in platelet aggregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of heterotypic cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of peptide hormone secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of fibrinogen complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fibrinogen alpha chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmur_3.0 Primary Assembly

    Genomic

    1. NC_033673.1 Reference Mmur_3.0 Primary Assembly

      Range
      49667596..49681583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012783641.1 → XP_012639095.1  fibrinogen alpha chain

      UniProtKB/TrEMBL
      A0A8C5UP64
      Related
      ENSMICP00000002931.2, ENSMICT00000003231.3
      Conserved Domains (3) summary
      cd00087
      Location:631 → 867
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
      pfam08702
      Location:50 → 187
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam12160
      Location:446 → 510
      Fibrinogen_aC; Fibrinogen alpha C domain
    Nucleotide Protein
    Heading Accession and Version

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