znf238.2.L zinc finger protein 238, gene 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: znf238.2.L
Official Full Name: zinc finger protein 238, gene 2 L homeolog
Primary source: Xenbase:XB-GENE-1219070
Locus tag: XELAEV_18039751mg
See related: AllianceGenome:Xenbase:XB-GENE-1219070
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: zbtb18.2; znf238.2
Summary: Predicted to enable DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and metal ion binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in musculoskeletal system; nervous system; and visual system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 22. Orthologous to human ZBTB18 (zinc finger and BTB domain containing 18). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8L

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (91075534..91082426)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (76346027..76351041)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger and BTB domain-containing protein 18.2

Names: Zinc finger protein 238.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086166.1 → NP_001079635.1 zinc finger and BTB domain-containing protein 18.2

See identical proteins and their annotated locations for NP_001079635.1

Status: PROVISIONAL

Source sequence(s)

BC046572

UniProtKB/TrEMBL

A0A974H8D6

Conserved Domains (5) summary

smart00225
Location:54 → 150

BTB; Broad-Complex, Tramtrack and Bric a brac

sd00017
Location:415 → 435

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00651
Location:43 → 147

BTB; BTB/POZ domain

pfam13465
Location:428 → 450

zf-H2C2_2; Zinc-finger double domain

pfam15909
Location:373 → 459

zf-C2H2_8; C2H2-type zinc ribbon

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

91075534..91082426

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018228601.2 → XP_018084090.1 zinc finger and BTB domain-containing protein 18.2 isoform X1

UniProtKB/Swiss-Prot

Q7ZWZ4

UniProtKB/TrEMBL

A0A8J0TE37