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    Vmn2r129 vomeronasal 2, receptor 129 [ Mus musculus (house mouse) ]

    Gene ID: 22314, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Vmn2r129provided by MGI
    Official Full Name
    vomeronasal 2, receptor 129provided by MGI
    Primary source
    MGI:MGI:1316735
    See related
    Ensembl:ENSMUSG00000057021 AllianceGenome:MGI:1316735
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    V2r8; V2r9; Vmn2r-ps159; Vmn2r-ps160
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. Is expressed in dorsal root ganglion. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r129 in Genome Data Viewer
    Location:
    4; 4 E2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (156683398..156691794)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (156331103..156339499)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor, 122 Neighboring gene predicted gene, 53275 Neighboring gene vomeronasal 2, receptor 125

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. FGF signalling controls expression of vomeronasal receptors during embryogenesis. Lioubinski O, et al. Mech Dev, 2006 Jan. PMID 16326081
    2. Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene. Göllner H, et al. Genes Cells, 2001 Aug. PMID 11532028
    3. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor 129
    Names
    vomeronasal 2, receptor, 8
    vomeronasal 2, receptor, 9
    vomeronasal 2, receptor, pseudogene 159
    vomeronasal 2, receptor, pseudogene 160
    vomeronasal organ family 2, receptor, 8
    vomeronasal organ family 2, receptor, 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001384510.1 → NP_001371439.1  vomeronasal 2, receptor 129 precursor

      Status: VALIDATED

      Source sequence(s)
      FP885536
      UniProtKB/TrEMBL
      A0A494B975, O35201
      Related
      ENSMUSP00000157509.2, ENSMUST00000074107.13
      Conserved Domains (1) summary
      cl10011
      Location:46 → 432
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    RNA

    1. NR_038052.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AF011418, AF011419
      Related
      ENSMUST00000189559.7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      156683398..156691794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163981.1 → XP_036019874.1  vomeronasal 2, receptor 129 isoform X2

      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Conserved Domains (3) summary
      cd15283
      Location:582 → 832
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:508 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_036163980.1 → XP_036019873.1  vomeronasal 2, receptor 129 isoform X1

      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Related
      ENSMUSP00000157307.2, ENSMUST00000096792.8
      Conserved Domains (3) summary
      cd15283
      Location:581 → 831
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:508 → 561
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    3. XM_036163982.1 → XP_036019875.1  vomeronasal 2, receptor 129 isoform X3

      UniProtKB/TrEMBL
      O35201
      Conserved Domains (1) summary
      cl10011
      Location:46 → 431
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_009494.1: Suppressed sequence

      Description
      NM_009494.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.

    2. NM_009495.1: Suppressed sequence

      Description
      NM_009495.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein Strain
    Heading Accession and Version

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