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    LOC109577316 HLA class II histocompatibility antigen, DM beta chain [ Bos indicus (zebu cattle) ]

    Gene ID: 109577316, updated on 14-Mar-2024

    Summary

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    Gene symbol
    LOC109577316
    Gene description
    HLA class II histocompatibility antigen, DM beta chain
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos indicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LOC109577316 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    100 current Bos_indicus_1.0 (GCF_000247795.1) 23 NC_032672.1 (7453547..7460406, complement)

    Chromosome 23 - NC_032672.1Genomic Context describing neighboring genes Neighboring gene transporter 1, ATP binding cassette subfamily B member Neighboring gene proteasome 20S subunit beta 9 Neighboring gene histone H2B type 1-like Neighboring gene HLA class II histocompatibility antigen, DM alpha chain Neighboring gene bromodomain containing 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_032672.1 Chromosome 23 Reference Bos_indicus_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A preliminary sketch of horn cancer transcriptome in Indian zebu cattle. Tripathi AK, et al. Gene, 2012 Feb 1. PMID 22134011

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MHC class II protein complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immunoglobulin production involved in immunoglobulin-mediated immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptide antigen assembly with MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    HLA class II histocompatibility antigen, DM beta chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Bos_indicus_1.0 Primary Assembly

    Genomic

    1. NC_032672.1 Reference Bos_indicus_1.0 Primary Assembly

      Range
      7453547..7460406 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_019986209.1 → XP_019841768.1  HLA class II histocompatibility antigen, DM beta chain isoform X1

      UniProtKB/TrEMBL
      A0A6P5DTN7
      Conserved Domains (2) summary
      cl03042
      Location:27 → 105
      MHC_II_beta; Class II histocompatibility antigen, beta domain
      cl11960
      Location:115 → 208
      Ig; Immunoglobulin domain

    2. XM_019986211.1 → XP_019841770.1  HLA class II histocompatibility antigen, DM beta chain isoform X3

      UniProtKB/TrEMBL
      A0A6P5DXI0
      Conserved Domains (2) summary
      cl03042
      Location:1 → 45
      MHC_II_beta; Class II histocompatibility antigen, beta domain
      cl11960
      Location:55 → 148
      Ig; Immunoglobulin domain

    3. XM_019986210.1 → XP_019841769.1  HLA class II histocompatibility antigen, DM beta chain isoform X2

      UniProtKB/TrEMBL
      A0A6P5DV06
      Conserved Domains (2) summary
      cl03042
      Location:27 → 105
      MHC_II_beta; Class II histocompatibility antigen, beta domain
      cl11960
      Location:115 → 209
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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