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    VWF von Willebrand factor [ Microcebus murinus (gray mouse lemur) ]

    Gene ID: 105869041, updated on 13-Mar-2024

    Summary

    Gene symbol
    VWF
    Gene description
    von Willebrand factor
    See related
    Ensembl:ENSMICG00000004782
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcebus murinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
    Orthologs
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    Genomic context

    See VWF in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    101 current Mmur_3.0 (GCF_000165445.2) 7 NC_033666.1 (104785972..104931971)
    100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012204907.1 (3045105..3191187)

    Chromosome 7 - NC_033666.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105869054 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene CD9 molecule Neighboring gene anoctamin-2-like Neighboring gene anoctamin-2

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell-substrate adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmur_3.0 Primary Assembly

    Genomic

    1. NC_033666.1 Reference Mmur_3.0 Primary Assembly

      Range
      104785972..104931971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012760580.1XP_012616034.1  von Willebrand factor

      UniProtKB/TrEMBL
      A0A8B7G3C3, A0A8C5UWZ7
      Related
      ENSMICP00000004374.2, ENSMICT00000004801.3
      Conserved Domains (12) summary
      smart00041
      Location:27462827
      CT; C-terminal cystine knot-like domain (CTCK)
      smart00214
      Location:24502513
      VWC; von Willebrand factor (vWF) type C domain
      smart00215
      Location:374418
      VWC_out; von Willebrand factor (vWF) type C domain
      smart00216
      Location:401564
      VWD; von Willebrand factor (vWF) type D domain
      smart00832
      Location:10771151
      C8; This domain contains 8 conserved cysteine residues
      cd01450
      Location:15161664
      vWFA_subfamily_ECM; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
      pfam00092
      Location:17101881
      VWA; von Willebrand factor type A domain
      pfam00094
      Location:19692121
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:319372
      TIL; Trypsin Inhibitor like cysteine rich domain
      pfam08742
      Location:21552218
      C8; C8 domain
      pfam16164
      Location:12221300
      VWA_N2; VWA N-terminal
      cl17735
      Location:26012663
      VWC; von Willebrand factor type C domain