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    VWF von Willebrand factor [ Microcebus murinus (gray mouse lemur) ]

    Gene ID: 105869041, updated on 13-Mar-2024

    Summary

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    Gene symbol
    VWF
    Gene description
    von Willebrand factor
    See related
    Ensembl:ENSMICG00000004782
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcebus murinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
    Orthologs
    human mouse all
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    Genomic context

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    See VWF in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    101 current Mmur_3.0 (GCF_000165445.2) 7 NC_033666.1 (104785972..104931971)
    100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012204907.1 (3045105..3191187)

    Chromosome 7 - NC_033666.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105869054 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene CD9 molecule Neighboring gene anoctamin-2-like Neighboring gene anoctamin-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-substrate adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    von Willebrand factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmur_3.0 Primary Assembly

    Genomic

    1. NC_033666.1 Reference Mmur_3.0 Primary Assembly

      Range
      104785972..104931971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012760580.1 → XP_012616034.1  von Willebrand factor

      UniProtKB/TrEMBL
      A0A8B7G3C3, A0A8C5UWZ7
      Related
      ENSMICP00000004374.2, ENSMICT00000004801.3
      Conserved Domains (12) summary
      smart00041
      Location:2746 → 2827
      CT; C-terminal cystine knot-like domain (CTCK)
      smart00214
      Location:2450 → 2513
      VWC; von Willebrand factor (vWF) type C domain
      smart00215
      Location:374 → 418
      VWC_out; von Willebrand factor (vWF) type C domain
      smart00216
      Location:401 → 564
      VWD; von Willebrand factor (vWF) type D domain
      smart00832
      Location:1077 → 1151
      C8; This domain contains 8 conserved cysteine residues
      cd01450
      Location:1516 → 1664
      vWFA_subfamily_ECM; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
      pfam00092
      Location:1710 → 1881
      VWA; von Willebrand factor type A domain
      pfam00094
      Location:1969 → 2121
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:319 → 372
      TIL; Trypsin Inhibitor like cysteine rich domain
      pfam08742
      Location:2155 → 2218
      C8; C8 domain
      pfam16164
      Location:1222 → 1300
      VWA_N2; VWA N-terminal
      cl17735
      Location:2601 → 2663
      VWC; von Willebrand factor type C domain
    Nucleotide Protein
    Heading Accession and Version

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