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    CAMK2G calcium/calmodulin dependent protein kinase II gamma [ Bos taurus (domestic cattle) ]

    Gene ID: 282162, updated on 10-Oct-2024

    Summary

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    Official Symbol
    CAMK2Gprovided by VGNC
    Official Full Name
    calcium/calmodulin dependent protein kinase II gammaprovided by VGNC
    Primary source
    VGNC:VGNC:55982
    See related
    BGD:BT10349; Ensembl:ENSBTAG00000012667
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See CAMK2G in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (29705565..29760907, complement)

    Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene zinc finger SWIM-type containing 8 Neighboring gene N-deacetylase and N-sulfotransferase 2 Neighboring gene plasminogen activator, urokinase Neighboring gene vinculin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C). Wolfe JT, et al. J Physiol, 2002 Jan 15. PMID 11790804, Free PMC Article
    2. Role of CaMKII in hydrogen peroxide activation of ERK1/2, p38 MAPK, HSP27 and actin reorganization in endothelial cells. Nguyen A, et al. FEBS Lett, 2004 Aug 13. PMID 15304367
    3. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. Aromolaran AS, et al. Am J Physiol Cell Physiol, 2007 Jul. PMID 17344311
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Redox-sensitive activation of p38 MAPK/HSP27 pathway or ERK1/2 in endothelial cells requires CaMKII
      Title: Role of CaMKII in hydrogen peroxide activation of ERK1/2, p38 MAPK, HSP27 and actin reorganization in endothelial cells.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium/calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit gamma
    Names
    calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
    NP_001091033.1
    XP_024842302.1
    XP_024842305.1
    XP_024842306.1
    XP_024842307.1
    XP_024842309.1
    XP_024842310.1
    XP_024842311.1
    XP_024842313.1
    XP_024842314.1
    XP_024842316.1
    XP_024842321.1
    XP_024842322.1
    XP_059738417.1
    XP_059738418.1
    XP_059738419.1
    XP_059738420.1
    XP_059738421.1
    XP_059738422.1
    XP_059738424.1
    XP_059738425.1
    XP_059738426.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001097564.1 → NP_001091033.1  calcium/calmodulin-dependent protein kinase type II subunit gamma

      See identical proteins and their annotated locations for NP_001091033.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123862
      UniProtKB/TrEMBL
      A0A3Q1M9U4, A4FV87
      Related
      ENSBTAP00000031271.5, ENSBTAT00000031316.6
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:363 → 490
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29705565..29760907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024986553.2 → XP_024842321.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X20

      UniProtKB/TrEMBL
      A0A3Q1M9U4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 295
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:355 → 482
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    2. XM_059882441.1 → XP_059738424.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X18

    3. XM_059882438.1 → XP_059738421.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X10

    4. XM_059882434.1 → XP_059738417.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X2

    5. XM_059882436.1 → XP_059738419.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X6

    6. XM_024986543.2 → XP_024842311.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X13

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:401 → 528
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    7. XM_024986546.2 → XP_024842314.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X16

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:386 → 513
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    8. XM_024986538.2 → XP_024842306.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X7

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Related
      ENSBTAP00000063192.2, ENSBTAT00000078262.2
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:424 → 551
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    9. XM_059882442.1 → XP_059738425.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X19

    10. XM_024986541.2 → XP_024842309.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X11

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:412 → 539
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    11. XM_059882439.1 → XP_059738422.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X14

    12. XM_059882435.1 → XP_059738418.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X4

    13. XM_024986548.2 → XP_024842316.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X17

      UniProtKB/TrEMBL
      A0A3Q1M9U4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:384 → 511
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    14. XM_024986539.2 → XP_024842307.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X8

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:422 → 549
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    15. XM_024986542.2 → XP_024842310.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X12

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:407 → 534
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    16. XM_024986534.2 → XP_024842302.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:445 → 572
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    17. XM_024986545.2 → XP_024842313.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X15

      UniProtKB/TrEMBL
      A0A3Q1M9U4, A0A3Q1N6D2
      Related
      ENSBTAP00000066000.2, ENSBTAT00000071058.2
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:395 → 522
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    18. XM_024986537.2 → XP_024842305.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5

      UniProtKB/TrEMBL
      A0A3Q1N1Z3
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:433 → 560
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    19. XM_059882437.1 → XP_059738420.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X9

    20. XM_024986554.2 → XP_024842322.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N1Z3, A0A3Q1NKC2
      Related
      ENSBTAP00000072771.2, ENSBTAT00000071649.2
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:456 → 583
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    21. XM_059882443.1 → XP_059738426.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X21

    RNA

    1. XR_009493215.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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