U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    ORF64 ORF64 [ Human gammaherpesvirus 8 ]

    Gene ID: 4961441, updated on 18-Aug-2023

    Summary

    Go to the top of the page Help
    Gene symbol
    ORF64
    Gene description
    ORF64
    Locus tag
    HHV8GK18_gp72
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Human gammaherpesvirus 8 (strain: GK18, type: P, common: Kaposi's sarcoma-associated herpesvirus, acronym: HHV-8, acronym: KSHV, nat-host: Homo sapiens)
    Lineage
    Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_009333.1 (104106..112013)

    NC_009333.1Genomic Context describing neighboring genes Neighboring gene vIRF-2 Neighboring gene ORF58 Neighboring gene ORF60 Neighboring gene ORF61 Neighboring gene ORF59 Neighboring gene ORF62 Neighboring gene ORF63 Neighboring gene ORF67A Neighboring gene ORF65 Neighboring gene ORF66 Neighboring gene ORF67 Neighboring gene ORF68 Neighboring gene ORF69 Neighboring gene K12

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_009333.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Inhibition of RIG-I-mediated signaling by Kaposi's sarcoma-associated herpesvirus-encoded deubiquitinase ORF64. Inn KS, et al. J Virol, 2011 Oct. PMID 21835791, Free PMC Article
    2. Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1. Gastaldello S, et al. J Mol Cell Biol, 2012 Aug. PMID 22474075
    3. Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome. Gupta S, et al. PLoS Pathog, 2018 Jan. PMID 29357390, Free PMC Article
    4. Kaposi's sarcoma-associated herpesvirus immune modulation: an overview. Rezaee SAR, et al. J Gen Virol, 2006 Jul. PMID 16760382

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    regulatory

    • Loc: 111992-111997 regulatory_class = polyA_signal_sequence

    General protein information

    Go to the top of the page Help
    Preferred Names
    ORF64
    YP_001129421.1
    • herpesvirus core gene UL36 family

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009333.1 Reference assembly

      Range
      104106..112013
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_001129421.1 ORF64 [Human gammaherpesvirus 8]

      See identical proteins and their annotated locations for YP_001129421.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q2HR64
      UniProtKB/TrEMBL
      A0A7D3QGU7, A0A7D5FQZ2, A0A7D5JP69, D0UZT1, K0FHU5, O40942, P88955
      Conserved Domains (3) summary
      TIGR00618
      Location:1385 → 1646
      sbcc; exonuclease SbcC
      PHA03247
      Location:2164 → 2484
      PHA03247; large tegument protein UL36; Provisional
      pfam04843
      Location:13 → 186
      Herpes_teg_N; Herpesvirus tegument protein, N-terminal conserved region
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.