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    LBRM_11_0850 putative pretranslocation protein, alpha subunit [ Leishmania braziliensis MHOM/BR/75/M2904 ]

    Gene ID: 5413509, updated on 30-Oct-2024

    Summary

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    Gene symbol
    LBRM_11_0850
    Gene description
    putative pretranslocation protein, alpha subunit
    Locus tag
    LBRM_11_0850
    Gene type
    protein coding
    RNA name
    putative pretranslocation protein, alpha subunit
    RefSeq status
    PROVISIONAL
    Organism
    Leishmania braziliensis MHOM/BR/75/M2904 (strain: MHOM/BR/75/M2904)
    Lineage
    Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania braziliensis species complex
    Orthologs
    Leishmania major all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    1
    Sequence:
    Chromosome: 11; NC_009303.2 (397366..398826)

    Chromosome 11 - NC_009303.2Genomic Context describing neighboring genes Neighboring gene conserved hypothetical protein Neighboring gene conserved hypothetical protein Neighboring gene putative zinc finger domain protein Neighboring gene putative zinc finger domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009303.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative genomic analysis of three Leishmania species that cause diverse human disease. Peacock CS, et al. Nat Genet, 2007 Jul. PMID 17572675, Free PMC Article
    2. Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Rogers MB, et al. Genome Res, 2011 Dec. PMID 22038252, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signal sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane, translocation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in post-translational protein targeting to membrane, translocation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Sec61 translocon complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Names
    putative pretranslocation protein, alpha subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009303.2 Reference assembly

      Range
      397366..398826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001562968.1 → XP_001563018.1  putative pretranslocation protein, alpha subunit [Leishmania braziliensis MHOM/BR/75/M2904]

      See identical proteins and their annotated locations for XP_001563018.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3P3Z099, A4H6N1
      Conserved Domains (3) summary
      PTZ00219
      Location:1 → 480
      PTZ00219; Sec61 alpha subunit; Provisional
      pfam00344
      Location:77 → 466
      SecY; SecY translocase
      pfam10559
      Location:42 → 75
      Plug_translocon; Plug domain of Sec61p
    Nucleotide Protein
    Heading Accession and Version

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