alyref Aly/REF export factor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: alyrefprovided by ZNC
Official Full Name: Aly/REF export factorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070928-29
See related: Ensembl:ENSDARG00000077732 AllianceGenome:ZFIN:ZDB-GENE-070928-29
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tho4; thoc4; zgc:171753
Summary: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be active in nucleus. Orthologous to human ALYREF (Aly/REF export factor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (59880208..59890529)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (59589107..59599428)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

fk41c01.x1 (e-PCR)
- UniSTS:200983

fk86a04.x1 (e-PCR)
- UniSTS:201640

fc22h08.x1 (e-PCR)
- UniSTS:187824

fj77c08.y1 (e-PCR)
- UniSTS:199861

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: THO complex subunit 4

Names: THO complex 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001105108.1 → NP_001098578.1 THO complex subunit 4

See identical proteins and their annotated locations for NP_001098578.1

Status: PROVISIONAL

Source sequence(s)

BC151964

UniProtKB/TrEMBL

A7MBY2

Related

ENSDARP00000103201.1, ENSDART00000108647.4

Conserved Domains (2) summary

COG0724
Location:126 → 226

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12680
Location:126 → 199

RRM_THOC4; RNA recognition motif in THO complex subunit 4 (THOC4) and similar proteins