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    gabra4 gamma-aminobutyric acid type A receptor subunit alpha4 [ Scleropages formosus (Asian bonytongue) ]

    Gene ID: 108938680, updated on 14-Mar-2024

    Summary

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    Gene symbol
    gabra4
    Gene description
    gamma-aminobutyric acid type A receptor subunit alpha4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Scleropages formosus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala; Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages
    Orthologs
    human zebrafish all
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    Genomic context

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    See gabra4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current fSclFor1.1 (GCF_900964775.1) 5 NC_041810.1 (16367466..16389157)
    100 previous assembly ASM162426v1 (GCF_001624265.1) Unplaced Scaffold NW_017372063.1 (5663793..5685354)

    Chromosome 5 - NC_041810.1Genomic Context describing neighboring genes Neighboring gene dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide-like Neighboring gene gamma-aminobutyric acid receptor subunit beta-1-like Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha2 Neighboring gene uncharacterized LOC108938745

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GABA-A receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GABA-gated chloride ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables benzodiazepine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inhibitory extracellular ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gamma-aminobutyric acid signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, GABAergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GABA-A receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-aminobutyric acid receptor subunit alpha-6
    Names
    gamma-aminobutyric acid type A receptor alpha4 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Scleropages formosus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fSclFor1.1 Primary Assembly

    Genomic

    1. NC_041810.1 Reference fSclFor1.1 Primary Assembly

      Range
      16367466..16389157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018759503.2 → XP_018615019.2  gamma-aminobutyric acid receptor subunit alpha-6 isoform X1

      Conserved Domains (3) summary
      pfam02932
      Location:448 → 736
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
      cd19037
      Location:242 → 440
      LGIC_ECD_GABAAR_A4; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-4 (GABAAR-A4 or GABRA4)
      cd19052
      Location:443 → 535
      LGIC_TM_GABAAR_alpha; transmembrane domain of alpha subunits of type-A gamma-aminobutyric acid receptor (GABAAR)

    2. XM_018759505.2 → XP_018615021.2  gamma-aminobutyric acid receptor subunit alpha-6 isoform X2

      Conserved Domains (3) summary
      pfam02932
      Location:448 → 735
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
      cd19037
      Location:242 → 440
      LGIC_ECD_GABAAR_A4; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-4 (GABAAR-A4 or GABRA4)
      cd19052
      Location:443 → 535
      LGIC_TM_GABAAR_alpha; transmembrane domain of alpha subunits of type-A gamma-aminobutyric acid receptor (GABAAR)

    3. XM_029252476.1 → XP_029108309.1  gamma-aminobutyric acid receptor subunit alpha-6 isoform X3

      Conserved Domains (3) summary
      pfam02932
      Location:426 → 714
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
      cd19037
      Location:220 → 418
      LGIC_ECD_GABAAR_A4; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-4 (GABAAR-A4 or GABRA4)
      cd19052
      Location:421 → 513
      LGIC_TM_GABAAR_alpha; transmembrane domain of alpha subunits of type-A gamma-aminobutyric acid receptor (GABAAR)
    Nucleotide Protein
    Heading Accession and Version

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