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    eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 [ Scleropages formosus (Asian bonytongue) ]

    Gene ID: 108927142, updated on 14-Mar-2024

    Summary

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    Gene symbol
    eif2ak2
    Gene description
    eukaryotic translation initiation factor 2-alpha kinase 2
    See related
    Ensembl:ENSSFOG00015008993
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Scleropages formosus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala; Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages
    Orthologs
    human zebrafish all
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    Genomic context

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    See eif2ak2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    101 current fSclFor1.1 (GCF_900964775.1) 4 NC_041809.1 (2460595..2473699)
    100 previous assembly ASM162426v1 (GCF_001624265.1) Unplaced Scaffold NW_017371582.1 (2362573..2375688, complement)

    Chromosome 4 - NC_041809.1Genomic Context describing neighboring genes Neighboring gene HEAT repeat containing 5B Neighboring gene G patch domain containing 11 Neighboring gene transfer RNA arginine (anticodon UCG) Neighboring gene protein kinase containing Z-DNA binding domains

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon-induced, double-stranded RNA-activated protein kinase-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Scleropages formosus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fSclFor1.1 Primary Assembly

    Genomic

    1. NC_041809.1 Reference fSclFor1.1 Primary Assembly

      Range
      2460595..2473699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018740247.2 → XP_018595763.2  interferon-induced, double-stranded RNA-activated protein kinase-like isoform X1

      UniProtKB/TrEMBL
      A0A8C9V160
      Related
      ENSSFOP00015013937.2, ENSSFOT00015014108.2
      Conserved Domains (3) summary
      smart00358
      Location:22 → 88
      DSRM; Double-stranded RNA binding motif
      cd00048
      Location:215 → 278
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
      cl21453
      Location:378 → 654
      PKc_like; Protein Kinases, catalytic domain

    2. XM_018740248.2 → XP_018595764.2  interferon-induced, double-stranded RNA-activated protein kinase-like isoform X2

      UniProtKB/TrEMBL
      A0A0P7VSM6
      Conserved Domains (3) summary
      smart00358
      Location:6 → 72
      DSRM; Double-stranded RNA binding motif
      cd00048
      Location:199 → 262
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
      cl21453
      Location:362 → 638
      PKc_like; Protein Kinases, catalytic domain

    3. XM_018740249.2 → XP_018595765.2  interferon-induced, double-stranded RNA-activated protein kinase-like isoform X2

      UniProtKB/TrEMBL
      A0A0P7VSM6
      Conserved Domains (3) summary
      smart00358
      Location:6 → 72
      DSRM; Double-stranded RNA binding motif
      cd00048
      Location:199 → 262
      DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
      cl21453
      Location:362 → 638
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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