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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 5848745, updated on 2-Nov-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000028515
    Locus tag
    YPR170W-B
    See related
    AllianceGenome:SGD:S000028515; FungiDB:YPR170W-B; VEuPathDB:YPR170W-B
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable RNA endonuclease activity. Predicted to be located in endoplasmic reticulum membrane and vacuolar membrane. Orthologous to human RNASEK (ribonuclease K). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    2
    Sequence:
    Chromosome: XVI; NC_001148.4 (883239..883595)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Jip5p Neighboring gene tRNA-Ile Neighboring gene Bsp1p Neighboring gene pyridoxal 5'-phosphate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Brachat S, et al. Genome Biol, 2003. PMID 12844361, Free PMC Article
    2. Structural basis of V-ATPase V(O) region assembly by Vma12p, 21p, and 22p. Wang H, et al. Proc Natl Acad Sci U S A, 2023 Feb 7. PMID 36724250, Free PMC Article
    3. Atomic model for the membrane-embedded V(O) motor of a eukaryotic V-ATPase. Mazhab-Jafari MT, et al. Nature, 2016 Nov 3. PMID 27776355, Free PMC Article
    4. Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae. He C, et al. J Proteome Res, 2018 Jul 6. PMID 29897761
    5. Transcriptome-wide binding sites for components of the Saccharomyces cerevisiae non-poly(A) termination pathway: Nrd1, Nab3, and Sen1. Creamer TJ, et al. PLoS Genet, 2011 Oct. PMID 22028667, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_001106949.1
    • Putative, non-essential component vacuolar ATPase; conserved in fungi; SWAT-GFP fusion protein localizes to vacuole membrane; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      883239..883595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184525.1 → NP_001106949.1  TPA: uncharacterized protein YPR170W-B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_001106949.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W4H1, P0C5R9
      UniProtKB/TrEMBL
      C7GP53, C8ZJJ8, N1P2H3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C5R9.1

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