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    GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [ Sarcophilus harrisii (Tasmanian devil) ]

    Gene ID: 100925249, updated on 8-Mar-2024

    Summary

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    Gene symbol
    GART
    Gene description
    phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
    See related
    Ensembl:ENSSHAG00000008555
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sarcophilus harrisii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
    Orthologs
    human mouse all
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    Genomic context

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    See GART in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current mSarHar1.11 (GCF_902635505.1) 3 NC_045428.1 (243950321..243992601)
    102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 3 Unlocalized Scaffold NW_003831547.1 (434876..477050)

    Chromosome 3 - NC_045428.1Genomic Context describing neighboring genes Neighboring gene crystallin zeta like 1 Neighboring gene DNA replication fork stabilization factor DONSON Neighboring gene SON DNA and RNA binding protein Neighboring gene DnaJ heat shock protein family (Hsp40) member C28 Neighboring gene transmembrane protein 50B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphoribosylamine-glycine ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphoribosylformylglycinamidine cyclo-ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphoribosylglycinamide formyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 'de novo' IMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trifunctional purine biosynthetic protein adenosine-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mSarHar1.11 Primary Assembly

    Genomic

    1. NC_045428.1 Reference mSarHar1.11 Primary Assembly

      Range
      243950321..243992601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031959339.1 → XP_031815199.1  trifunctional purine biosynthetic protein adenosine-3 isoform X3

      Conserved Domains (1) summary
      PRK00885
      Location:5 → 427
      PRK00885; phosphoribosylamine--glycine ligase; Provisional

    2. XM_012544398.3 → XP_012399852.1  trifunctional purine biosynthetic protein adenosine-3 isoform X1

      UniProtKB/TrEMBL
      G3W376
      Related
      ENSSHAP00000009881.1, ENSSHAT00000009968.2
      Conserved Domains (3) summary
      cd08645
      Location:812 → 993
      FMT_core_GART; Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART)
      PRK00885
      Location:5 → 427
      PRK00885; phosphoribosylamine--glycine ligase; Provisional
      PRK05385
      Location:436 → 767
      PRK05385; phosphoribosylaminoimidazole synthetase; Provisional

    3. XM_031959338.1 → XP_031815198.1  trifunctional purine biosynthetic protein adenosine-3 isoform X2

      UniProtKB/TrEMBL
      A0A7N4NKQ6
      Related
      ENSSHAP00000024840.1, ENSSHAT00000039411.1
      Conserved Domains (3) summary
      cd08645
      Location:780 → 961
      FMT_core_GART; Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART)
      PRK00885
      Location:5 → 395
      PRK00885; phosphoribosylamine--glycine ligase; Provisional
      PRK05385
      Location:404 → 735
      PRK05385; phosphoribosylaminoimidazole synthetase; Provisional

    4. XM_023498894.2 → XP_023354662.1  trifunctional purine biosynthetic protein adenosine-3 isoform X1

      UniProtKB/TrEMBL
      G3W376
      Conserved Domains (3) summary
      cd08645
      Location:812 → 993
      FMT_core_GART; Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART)
      PRK00885
      Location:5 → 427
      PRK00885; phosphoribosylamine--glycine ligase; Provisional
      PRK05385
      Location:436 → 767
      PRK05385; phosphoribosylaminoimidazole synthetase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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