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    Pten phosphatase and tensin-like protein [ Drosophila miranda ]

    Gene ID: 108161604, updated on 23-May-2024

    Summary

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    Gene symbol
    Pten
    Gene description
    phosphatase and tensin-like protein
    See related
    EnsemblRapid:LOC108161604
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Drosophila miranda
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Orthologs
    fruit fly all
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    Genomic context

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    See Pten in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    102 current D.miranda_PacBio2.1 (GCF_003369915.1) 4 NC_046677.1 (19469935..19487425)
    101 previous assembly DroMir_2.2 (GCF_000269505.1) 4 NC_030306.1 (15686886..15705006)

    Chromosome 4 - NC_046677.1Genomic Context describing neighboring genes Neighboring gene tyrosine-protein kinase transmembrane receptor Ror Neighboring gene elongation factor 1-delta Neighboring gene defective proboscis extension response 21 Neighboring gene FERM domain containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Drosophila miranda Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference D.miranda_PacBio2.1

    Genomic

    1. NC_046677.1 Reference D.miranda_PacBio2.1

      Range
      19469935..19487425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033393607.1 → XP_033249498.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1

      UniProtKB/TrEMBL
      A0AA97IQ07
      Related
      XP_033249498.1, XM_033393607.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    2. XM_017295891.2 → XP_017151380.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1

      UniProtKB/TrEMBL
      A0AA97IQ07
      Related
      XP_017151380.1, XM_017295891.2
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    3. XM_033393608.1 → XP_033249499.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1

      UniProtKB/TrEMBL
      A0AA97IQ07
      Related
      XP_033249499.1, XM_033393608.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    4. XM_017295892.2 → XP_017151381.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1

      UniProtKB/TrEMBL
      A0AA97IQ07
      Related
      XP_017151381.1, XM_017295892.2
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    5. XM_033393609.1 → XP_033249500.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2

      UniProtKB/TrEMBL
      A0AA97IQ07
      Related
      XP_033249500.1, XM_033393609.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    6. XM_033393612.1 → XP_033249503.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3

      UniProtKB/TrEMBL
      A0AA97IQ07, A0AA97IQ11
      Related
      XP_033249503.1, XM_033393612.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    7. XM_033393611.1 → XP_033249502.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3

      UniProtKB/TrEMBL
      A0AA97IQ07, A0AA97IQ11
      Related
      XP_033249502.1, XM_033393611.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    8. XM_033393614.1 → XP_033249505.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X4

      UniProtKB/TrEMBL
      A0AA97IQ12
      Related
      XP_033249505.1, XM_033393614.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    9. XM_033393613.1 → XP_033249504.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X4

      UniProtKB/TrEMBL
      A0AA97IQ12
      Related
      XP_033249504.1, XM_033393613.1
      Conserved Domains (2) summary
      cd14509
      Location:31 → 189
      PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
      pfam10409
      Location:196 → 336
      PTEN_C2; C2 domain of PTEN tumor-suppressor protein

    RNA

    1. XR_004473009.1 RNA Sequence

      Related
      XR_004473009.1
    Nucleotide Protein Strain
    Heading Accession and Version

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