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    ESR1 estrogen receptor 1 [ Mirounga leonina (Southern elephant seal) ]

    Gene ID: 118001078, updated on 19-Jun-2024

    Summary

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    Gene symbol
    ESR1
    Gene description
    estrogen receptor 1
    See related
    EnsemblRapid:ENSMLOG00005005503
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mirounga leonina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Mirounga
    Orthologs
    human mouse all
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    Genomic context

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    See ESR1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    100 current KU_Mleo_1.0 (GCF_011800145.1) Unplaced Scaffold NW_023270807.1 (101384180..101771511)

    NW_023270807.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 170 Neighboring gene uncharacterized LOC118001080 Neighboring gene homeobox protein NANOG-like Neighboring gene uncharacterized LOC118001082 Neighboring gene spectrin repeat containing nuclear envelope protein 1 Neighboring gene MYC target 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023270807 Unplaced Scaffold Reference KU_Mleo_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear estrogen receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in steroid hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    estrogen receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mirounga leonina Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KU_Mleo_1.0 Primary Assembly

    Genomic

    1. NW_023270807.1 Reference KU_Mleo_1.0 Primary Assembly

      Range
      101384180..101771511
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034991026.1 → XP_034846917.1  estrogen receptor

      Related
      ENSMLOP00005007660.1, ENSMLOT00005008750.1
      Conserved Domains (4) summary
      cd06949
      Location:310 → 547
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam02159
      Location:42 → 181
      Oest_recep; Oestrogen receptor
      pfam12743
      Location:556 → 595
      ESR1_C; Oestrogen-type nuclear receptor final C-terminal

    2. XM_034991025.1 → XP_034846916.1  estrogen receptor

      Conserved Domains (4) summary
      cd06949
      Location:310 → 547
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam02159
      Location:42 → 181
      Oest_recep; Oestrogen receptor
      pfam12743
      Location:556 → 595
      ESR1_C; Oestrogen-type nuclear receptor final C-terminal

    3. XM_034991028.1 → XP_034846919.1  estrogen receptor

      Conserved Domains (4) summary
      cd06949
      Location:310 → 547
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam02159
      Location:42 → 181
      Oest_recep; Oestrogen receptor
      pfam12743
      Location:556 → 595
      ESR1_C; Oestrogen-type nuclear receptor final C-terminal

    4. XM_034991029.1 → XP_034846920.1  estrogen receptor

      Conserved Domains (4) summary
      cd06949
      Location:310 → 547
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam02159
      Location:42 → 181
      Oest_recep; Oestrogen receptor
      pfam12743
      Location:556 → 595
      ESR1_C; Oestrogen-type nuclear receptor final C-terminal
    Nucleotide Protein
    Heading Accession and Version

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