suclg2 succinate-CoA ligase GDP-forming subunit beta [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: suclg2provided by ZNC
Official Full Name: succinate-CoA ligase GDP-forming subunit betaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030114-3
See related: Ensembl:ENSDARG00000044914 AllianceGenome:ZFIN:ZDB-GENE-030114-3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb625; fd44e06; wu:fd44e06
Summary: Predicted to enable succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Predicted to be part of succinate-CoA ligase complex. Predicted to be active in mitochondrion. Is expressed in lens; liver; pronephric duct; solid lens vesicle; and yolk syncytial layer. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (16738158..16975078, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (16603523..16840447, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI477919 (e-PCR)
- UniSTS:206431

fb64e03 (e-PCR)
- UniSTS:189054

G47384 (e-PCR)
- UniSTS:108165

G39617 (e-PCR)
- UniSTS:29597

G46666 (e-PCR)
- UniSTS:107466

G44889 (e-PCR)
- UniSTS:105691

fb49a07.x1 (e-PCR)
- UniSTS:203235

fb68a03.y1 (e-PCR)
- UniSTS:190961

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables succinate-CoA ligase (GDP-forming) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within succinyl-CoA metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info
involved_in tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

Names: SUCLGb; succinate-CoA ligase, GDP-forming, beta subunit; succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial

NP_001373238.1

EC 6.2.1.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001386309.1 → NP_001373238.1 succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

Status: VALIDATED

Source sequence(s)

CR847506, CT955969

UniProtKB/TrEMBL

A0A8M1QKY6, A0A8M9QHZ9, F1R7X5

Related

ENSDARP00000107576.1, ENSDART00000122222.3

Conserved Domains (1) summary

PRK00696
Location:39 → 420

sucC; ADP-forming succinate--CoA ligase subunit beta