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    LF2 virion protein G11 [ Human gammaherpesvirus 4 (Epstein-Barr virus) ]

    Gene ID: 3783748, updated on 20-Nov-2023

    Summary

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    Gene symbol
    LF2
    Gene description
    virion protein G11
    Locus tag
    HHV4_LF2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Human gammaherpesvirus 4 (strain: B95-8, strain: Raji, type: 1, common: Epstein-Barr virus, acronym: EBV, acronym: HHV-4, nat-host: Homo sapiens)
    Lineage
    Viruses; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus
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    Genomic context

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    Sequence:
    NC_007605.1 (149025..150417, complement)

    NC_007605.1Genomic Context describing neighboring genes Neighboring gene membrane protein BILF2 Neighboring gene protein RPMS1 Neighboring gene protein LF3 Neighboring gene membrane protein BILF1 Neighboring gene protein G10 Neighboring gene DNA polymerase catalytic subunit Neighboring gene protein A73 Neighboring gene envelope glycoprotein B Neighboring gene DNA packaging terminase subunit 2 Neighboring gene protein BARF0

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007605.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Epstein-Barr virus LF2 protein regulates viral replication by altering Rta subcellular localization. Heilmann AM, et al. J Virol, 2010 Oct. PMID 20631124, Free PMC Article
    2. Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV. de Jesus O, et al. J Gen Virol, 2003 Jun. PMID 12771413
    3. The EB virus genome in Daudi Burkitt's lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus. Jones MD, et al. EMBO J, 1984 Apr. PMID 6327290, Free PMC Article
    4. Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript. Jeang KT, et al. J Virol, 1983 Oct. PMID 6310141, Free PMC Article
    5. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Baer R, et al. Nature, 1984 Jul 19-25. PMID 6087149

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. mapped the LF2 binding site to Rta amino acids (aa) 476 to 519 and showed that LF2 binding is critical for Rta relocalization and repression
      Title: Epstein-Barr virus LF2 protein regulates viral replication by altering Rta subcellular localization.
    Submit: New GeneRIF Correction

    General gene information

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    regulatory

    • Loc: c149030-149025 regulatory_class = polyA_signal_sequence
    • Loc: c150417-150412 regulatory_class = TATA_box

    General protein information

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    Preferred Names
    virion protein G11

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007605.1 Reference assembly

      Range
      149025..150417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_401708.1 virion protein G11 [Human gammaherpesvirus 4]

      See identical proteins and their annotated locations for YP_401708.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0C725, P0C726, Q99306
      UniProtKB/TrEMBL
      A0A075FF05, A0A075FGB4, A0A0B6VK83, A0A0C7THU0, A0A0C7TIL2, A0A0X8WER3, A0A1W5LUD3, A0A2D1LYL5, A0A2S1MMV5, A0A2S1MSC7, A0A2S1MUQ4, A0A2S1MV10, A0A2S1MWV7, A0A2S1N1N0, A0A385J8F5, A0A385J932, A0A3R5XI35, A0A3R5ZK92, A0A3R5ZZQ3, A0A410IPK9, A0A4D6TX62, I1YP59, K9US88, K9UTL9, V5KUD6
      Conserved Domains (1) summary
      PHA03365
      Location:4 → 421
      PHA03365; hypothetical protein; Provisional
    Nucleotide Protein
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