The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference assembly

Genomic

1. NC_025217.1 Reference assembly

   Range

   303..22045

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. YP_009072438.1 ORF1ab polyprotein [Bat Hp-betacoronavirus/Zhejiang2013]

   See identical proteins and their annotated locations for YP_009072438.1

   Status: PROVISIONAL

   UniProtKB/TrEMBL

   A0A088DIE1

   Conserved Domains (16) summary

   pfam11633
   Location:1478 → 1591

   SUD-M; Single-stranded poly(A) binding domain

   COG1112
   Location:5835 → 6055

   DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]

   pfam01661
   Location:1204 → 1301

   Macro; Macro domain

   pfam05409
   Location:3433 → 3710

   Peptidase_C30; Coronavirus endopeptidase C30

   pfam06460
   Location:6950 → 7246

   NSP13; Coronavirus NSP13

   pfam06471
   Location:6070 → 6663

   NSP11; NSP11

   pfam06478
   Location:4548 → 4900

   Corona_RPol_N; Coronavirus RPol N-terminus

   pfam08710
   Location:4285 → 4396

   nsp9; nsp9 replicase

   pfam08715
   Location:1682 → 1996

   Viral_protease; Papain like viral protease

   pfam08716
   Location:4004 → 4086

   nsp7; nsp7 replicase

   pfam08717
   Location:4087 → 4284

   nsp8; nsp8 replicase

   pfam09401
   Location:4410 → 4527

   NSP10; RNA synthesis protein NSP10

   pfam11501
   Location:13 → 126

   Nsp1; Non structural protein Nsp1

   pfam16348
   Location:3314 → 3402

   Corona_NSP4_C; Coronavirus nonstructural protein 4 C-terminus

   cl21455
   Location:5743 → 5873

   P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

   cl22977
   Location:5893 → 6046

   UvrD_C_2; UvrD-like helicase C-terminal domain

2. YP_009915659.1 ORF1a polyprotein [Bat Hp-betacoronavirus/Zhejiang2013]

   Status: PROVISIONAL

   Conserved Domains (17) summary

   cd21467
   Location:837 → 924

   Ubl1_cv_Nsp3_N-like; first ubiquitin-like (Ubl) domain located at the N-terminus of coronavirus SARS-CoV non-structural protein 3 (Nsp3) and related proteins

   cd21473
   Location:2917 → 3298

   cv_Nsp4_TM; coronavirus non-structural protein 4 (Nsp4) transmembrane domain

   cd21560
   Location:3711 → 4003

   betaCoV-Nsp6; betacoronavirus non-structural protein 6

   cd21516
   Location:177 → 814

   cv_beta_Nsp2_SARS-like; betacoronavirus non-structural protein 2 (Nsp2) similar to SARS-CoV Nsp2, and related proteins from betacoronaviruses in the B lineage

   cd21557
   Location:1200 → 1323

   Macro_X_Nsp3-like; X-domain of viral non-structural protein 3 and related macrodomains

   cd21563
   Location:1477 → 1598

   Macro_cv_SUD-M_Nsp3-like; SUD-M macrodomain of the SARS Unique Domain (SUD) of SARS-CoV non-structural protein 3 and related macrodomains

   cd21666
   Location:3408 → 3704

   betaCoV_Nsp5_Mpro; betacoronavirus non-structural protein 5, also called Main protease (Mpro)

   pfam11501
   Location:7 → 140

   Nsp1; Non structural protein Nsp1

   pfam16348
   Location:3314 → 3402

   Corona_NSP4_C; Coronavirus nonstructural protein 4 C-terminus

   cd21827
   Location:4004 → 4086

   betaCoV_Nsp7; betacoronavirus non-structural protein 7

   cd21831
   Location:4090 → 4284

   betaCoV_Nsp8; betacoronavirus non-structural protein 8

   cd21901
   Location:4397 → 4527

   alpha_betaCoV_Nsp10; alphacoronavirus and betacoronavirus non-structural protein 14

   cd21898
   Location:4285 → 4396

   betaCoV_Nsp9; betacoronavirus non-structural protein 9

   cd21822
   Location:2034 → 2147

   SARS-CoV-like_Nsp3_NAB; nucleic acid binding domain of non-structural protein 3 from Severe acute respiratory syndrome-related coronavirus and betacoronavirus in the B lineage

   cd21732
   Location:1682 → 1989

   betaCoV_PLPro; betacoronavirus papain-like protease

   cd21713
   Location:2353 → 2901

   TM_Y_betaCoV_Nsp3_C; C-terminus of betacoronavirus non-structural protein 3, including transmembrane and Y domains

   cl41743
   Location:2170 → 2278

   betaCoV_Nsp3_betaSM; betacoronavirus-specific marker of betacoronavirus non-structural protein 3