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    HSPG2 heparan sulfate proteoglycan 2 [ Cebus imitator (Panamanian white-faced capuchin) ]

    Gene ID: 108288120, updated on 14-Mar-2024

    Summary

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    Gene symbol
    HSPG2
    Gene description
    heparan sulfate proteoglycan 2
    See related
    Ensembl:ENSCCAG00000033733
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cebus imitator
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Cebinae; Cebus
    Orthologs
    human mouse all
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    Genomic context

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    See HSPG2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    102
    Annotation release Status Assembly Chr Location
    101 current Cebus_imitator-1.0 (GCF_001604975.1) Unplaced Scaffold NW_016107330.1 (12029081..12153089, complement)

    NW_016107330.1Genomic Context describing neighboring genes Neighboring gene HIG1 domain family member 2A, mitochondrial-like Neighboring gene refilin-B-like Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene U4 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene chymotrypsin like elastase 3B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_016107330 Unplaced Scaffold Reference Cebus_imitator-1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    basement membrane-specific heparan sulfate proteoglycan core protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cebus imitator Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cebus_imitator-1.0

    Genomic

    1. NW_016107330.1 Reference Cebus_imitator-1.0

      Range
      12029081..12153089 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017506939.2 → XP_017362428.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X7

      UniProtKB/TrEMBL
      A0A2K5RT75
      Related
      ENSCCAP00000031353.1, ENSCCAT00000049105.1

    2. XM_017506931.2 → XP_017362420.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X6

    3. XM_037730732.1 → XP_037586660.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X5

      Conserved Domains (16) summary
      cd05743
      Location:421 → 498
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
      smart00200
      Location:80 → 194
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      smart00281
      Location:590 → 716
      LamB; Laminin B domain
      smart00409
      Location:2085 → 2162
      IG; Immunoglobulin
      smart00410
      Location:3146 → 3227
      IG_like; Immunoglobulin like
      cd00054
      Location:3883 → 3912
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:1158 → 1207
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:4234 → 4393
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:285 → 319
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:4139 → 4169
      EGF; EGF-like domain
      pfam00052
      Location:990 → 1124
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1275 → 1322
      Laminin_EGF; Laminin EGF domain
      pfam07679
      Location:3601 → 3683
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:3603 → 3606
      Ig; Ig strand A [structural motif]
      cd05754
      Location:1799 → 1884
      IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:3430 → 3508
      Ig; Immunoglobulin domain

    4. XM_037730725.1 → XP_037586653.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X3

      Conserved Domains (16) summary
      cd05743
      Location:421 → 498
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
      smart00200
      Location:80 → 194
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      smart00281
      Location:590 → 716
      LamB; Laminin B domain
      smart00409
      Location:2481 → 2558
      IG; Immunoglobulin
      smart00410
      Location:2191 → 2268
      IG_like; Immunoglobulin like
      cd00054
      Location:3893 → 3922
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:1158 → 1207
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:4244 → 4403
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:285 → 319
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:4149 → 4179
      EGF; EGF-like domain
      pfam00052
      Location:990 → 1124
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1275 → 1322
      Laminin_EGF; Laminin EGF domain
      pfam07679
      Location:3611 → 3693
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:3613 → 3616
      Ig; Ig strand A [structural motif]
      cd05754
      Location:1905 → 1990
      IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:3440 → 3518
      Ig; Immunoglobulin domain

    5. XM_037730745.1 → XP_037586673.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X8

      Conserved Domains (16) summary
      cd05743
      Location:421 → 498
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
      smart00200
      Location:80 → 194
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      smart00281
      Location:590 → 716
      LamB; Laminin B domain
      smart00409
      Location:2191 → 2268
      IG; Immunoglobulin
      smart00410
      Location:3054 → 3135
      IG_like; Immunoglobulin like
      cd00054
      Location:3791 → 3820
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:1158 → 1207
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:4142 → 4301
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:285 → 319
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:4047 → 4077
      EGF; EGF-like domain
      pfam00052
      Location:990 → 1124
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1275 → 1322
      Laminin_EGF; Laminin EGF domain
      pfam07679
      Location:3509 → 3591
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:3511 → 3514
      Ig; Ig strand A [structural motif]
      cd05754
      Location:1905 → 1990
      IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:3338 → 3416
      Ig; Immunoglobulin domain

    6. XM_037730730.1 → XP_037586658.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X4

      Conserved Domains (16) summary
      cd05743
      Location:421 → 498
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
      smart00200
      Location:80 → 194
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      smart00281
      Location:590 → 716
      LamB; Laminin B domain
      smart00409
      Location:2191 → 2268
      IG; Immunoglobulin
      smart00410
      Location:3154 → 3235
      IG_like; Immunoglobulin like
      cd00054
      Location:3891 → 3920
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:1158 → 1207
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:4242 → 4401
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:285 → 319
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:4147 → 4177
      EGF; EGF-like domain
      pfam00052
      Location:990 → 1124
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1275 → 1322
      Laminin_EGF; Laminin EGF domain
      pfam07679
      Location:3609 → 3691
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:3611 → 3614
      Ig; Ig strand A [structural motif]
      cd05754
      Location:1905 → 1990
      IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:3438 → 3516
      Ig; Immunoglobulin domain

    7. XM_037730723.1 → XP_037586651.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

      Conserved Domains (16) summary
      cd05743
      Location:421 → 498
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
      smart00200
      Location:80 → 194
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      smart00281
      Location:590 → 716
      LamB; Laminin B domain
      smart00409
      Location:2385 → 2459
      IG; Immunoglobulin
      smart00410
      Location:2191 → 2268
      IG_like; Immunoglobulin like
      cd00054
      Location:3983 → 4012
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:1158 → 1207
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:4334 → 4493
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:285 → 319
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:4239 → 4269
      EGF; EGF-like domain
      pfam00052
      Location:990 → 1124
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1275 → 1322
      Laminin_EGF; Laminin EGF domain
      pfam07679
      Location:3707 → 3789
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:3709 → 3712
      Ig; Ig strand A [structural motif]
      cd05754
      Location:1905 → 1990
      IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:3536 → 3614
      Ig; Immunoglobulin domain

    8. XM_037730717.1 → XP_037586645.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

      Conserved Domains (16) summary
      cd05743
      Location:421 → 498
      Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
      smart00200
      Location:80 → 194
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      smart00281
      Location:590 → 716
      LamB; Laminin B domain
      smart00409
      Location:3252 → 3333
      IG; Immunoglobulin
      smart00410
      Location:2191 → 2268
      IG_like; Immunoglobulin like
      cd00054
      Location:3989 → 4018
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:1158 → 1207
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:4340 → 4499
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      cd00112
      Location:285 → 319
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00008
      Location:4245 → 4275
      EGF; EGF-like domain
      pfam00052
      Location:990 → 1124
      Laminin_B; Laminin B (Domain IV)
      pfam00053
      Location:1275 → 1322
      Laminin_EGF; Laminin EGF domain
      pfam07679
      Location:3707 → 3789
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:3709 → 3712
      Ig; Ig strand A [structural motif]
      cd05754
      Location:1905 → 1990
      IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      cl11960
      Location:3536 → 3614
      Ig; Immunoglobulin domain
    Nucleotide Protein
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