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    aplp2 amyloid beta (A4) precursor-like protein 2 [ Carcharodon carcharias (great white shark) ]

    Gene ID: 121269487, updated on 22-Mar-2024

    Summary

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    Gene symbol
    aplp2
    Gene description
    amyloid beta (A4) precursor-like protein 2
    See related
    EnsemblRapid:ENSCHSG00020012589
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Carcharodon carcharias
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Elasmobranchii; Galeomorphii; Galeoidea; Lamniformes; Alopiidae; Carcharodon
    Orthologs
    human zebrafish all
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    Genomic context

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    See aplp2 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    100 current sCarCar2.pri (GCF_017639515.1) 25 NC_054491.1 (47386131..47572432, complement)

    Chromosome 25 - NC_054491.1Genomic Context describing neighboring genes Neighboring gene pannexin 3 Neighboring gene suppressor of tumorigenicity 14 protein homolog Neighboring gene PR domain containing 10 Neighboring gene nuclear factor related to kappaB binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_054491.1 Chromosome 25 Reference sCarCar2.pri Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amyloid-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Carcharodon carcharias Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference sCarCar2.pri Primary Assembly

    Genomic

    1. NC_054491.1 Reference sCarCar2.pri Primary Assembly

      Range
      47386131..47572432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041174080.1 → XP_041030014.1  amyloid-like protein 2 isoform X2

      Conserved Domains (2) summary
      smart00006
      Location:55 → 219
      A4_EXTRA; amyloid A4
      cd00109
      Location:306 → 358
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    2. XM_041174079.1 → XP_041030013.1  amyloid-like protein 2 isoform X1

      Related
      ENSCHSP00020021670.1, ENSCHST00020023987.1
      Conserved Domains (2) summary
      smart00006
      Location:55 → 219
      A4_EXTRA; amyloid A4
      cd00109
      Location:306 → 358
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    3. XM_041174081.1 → XP_041030015.1  amyloid-like protein 2 isoform X3

      Related
      ENSCHSP00020021735.1, ENSCHST00020024060.1
      Conserved Domains (2) summary
      smart00006
      Location:55 → 219
      A4_EXTRA; amyloid A4
      cd00109
      Location:306 → 358
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    4. XM_041174082.1 → XP_041030016.1  amyloid-like protein 2 isoform X4

      Related
      ENSCHSP00020021797.1, ENSCHST00020024131.1
      Conserved Domains (1) summary
      smart00006
      Location:55 → 219
      A4_EXTRA; amyloid A4
    Nucleotide Protein
    Heading Accession and Version

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