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    ddhd2.L DDHD domain containing 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 779092, updated on 20-Nov-2024

    Summary

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    Official Symbol
    ddhd2.L
    Official Full Name
    DDHD domain containing 2 L homeolog
    Primary source
    Xenbase:XB-GENE-964278
    Locus tag
    XELAEV_18018816mg
    See related
    EnsemblRapid:ENSXLAG00005003730 AllianceGenome:Xenbase:XB-GENE-964278
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    ddhd2; ddhd2.S
    Summary
    Predicted to enable metal ion binding activity; phospholipase activity; and triacylglycerol lipase activity. Predicted to be located in COPII-coated ER to Golgi transport vesicle. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 54. Orthologous to human DDHD2 (DDHD domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ddhd2.L in Genome Data Viewer
    Location:
    chromosome: 3L
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (140665497..140689338, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (124504841..124523398, complement)

    Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding SET domain protein 3 L homeolog Neighboring gene phospholipid phosphatase 5 L homeolog Neighboring gene protein spinster homolog 1-like Neighboring gene NAD(P)(+)--arginine ADP-ribosyltransferase 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phospholipase DDHD2
    Names
    DDHD domain containing 2 S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      140665497..140689338 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041587106.1 → XP_041443040.1  phospholipase DDHD2 isoform X1

      UniProtKB/TrEMBL
      A0A8J1MPR7, A0JMW4
      Related
      ENSXLAP00005011125.1, ENSXLAT00005011298.1
      Conserved Domains (1) summary
      cd09585
      Location:385 → 453
      SAM_DDHD2; SAM domain of DDHD2

    2. XM_018253577.2 → XP_018109066.1  phospholipase DDHD2 isoform X2

      UniProtKB/TrEMBL
      A0A1L8H287, A0A974DDS1, A0JMW4
      Related
      ENSXLAP00005011121.1, ENSXLAT00005011295.1
    Nucleotide Protein Strain
    Heading Accession and Version

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