U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    OPA1 OPA1, mitochondrial dynamin like GTPase [ Gallus gallus (chicken) ]

    Gene ID: 424900, updated on 16-Jun-2024

    Summary

    Go to the top of the page Help
    Symbol
    OPA1provided by CGNC
    Full Name
    OPA1, mitochondrial dynamin like GTPaseprovided by CGNC
    Primary source
    CGNC:5403
    See related
    Ensembl:ENSGALG00010013663
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See OPA1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (12709489..12759332, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (12512367..12562210, complement)

    Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101750501 Neighboring gene hes family bHLH transcription factor 1 Neighboring gene ATPase 13A4 Neighboring gene ATPase 13A5

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    dynamin-like GTPase OPA1, mitochondrial; dynamin-like 120 kDa protein, mitochondrial
    Names
    optic atrophy 1 (autosomal dominant)
    optic atrophy protein 1 homolog
    NP_001034398.2
    NP_001383101.1
    NP_001383102.1
    NP_001383103.1
    NP_001383104.1
    XP_015146883.1
    XP_015146886.1
    XP_046754374.1
    XP_046779824.1
    XP_046779825.1
    XP_046779826.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039309.2 → NP_001034398.2  dynamin-like GTPase OPA1, mitochondrial isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      F1N8M4
      Related
      ENSGALP00010019501.1, ENSGALT00010032980.1
      Conserved Domains (1) summary
      cd08771
      Location:304 → 578
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    2. NM_001396172.1 → NP_001383101.1  dynamin-like GTPase OPA1, mitochondrial isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      R4GJ94
      Related
      ENSGALP00010019505.1, ENSGALT00010032994.1
      Conserved Domains (1) summary
      cd08771
      Location:323 → 597
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    3. NM_001396173.1 → NP_001383102.1  dynamin-like GTPase OPA1, mitochondrial isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      A0A1D5PM27
      Related
      ENSGALP00010019494.1, ENSGALT00010032965.1
      Conserved Domains (1) summary
      cd08771
      Location:341 → 615
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    4. NM_001396174.1 → NP_001383103.1  dynamin-like GTPase OPA1, mitochondrial isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      UniProtKB/Swiss-Prot
      Q5F499
      Conserved Domains (1) summary
      cd08771
      Location:286 → 560
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    5. NM_001396175.1 → NP_001383104.1  dynamin-like GTPase OPA1, mitochondrial isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000240
      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      F1N8M4
      Related
      ENSGALP00010019479.1, ENSGALT00010032928.1
      Conserved Domains (1) summary
      cd08771
      Location:304 → 578
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      12709489..12759332 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015291400.4 → XP_015146886.1  dynamin-like 120 kDa protein, mitochondrial isoform X3

      UniProtKB/Swiss-Prot
      Q5F499
      Conserved Domains (1) summary
      cd08771
      Location:286 → 560
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    2. XM_046898418.1 → XP_046754374.1  dynamin-like 120 kDa protein, mitochondrial isoform X2

      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      R4GJ94

    3. XM_015291397.4 → XP_015146883.1  dynamin-like 120 kDa protein, mitochondrial isoform X1

      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      A0A1D5PM27
      Conserved Domains (1) summary
      cd08771
      Location:341 → 615
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      12512367..12562210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046923870.1 → XP_046779826.1  dynamin-like 120 kDa protein, mitochondrial isoform X3

      UniProtKB/Swiss-Prot
      Q5F499

    2. XM_046923869.1 → XP_046779825.1  dynamin-like 120 kDa protein, mitochondrial isoform X2

      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      R4GJ94

    3. XM_046923868.1 → XP_046779824.1  dynamin-like 120 kDa protein, mitochondrial isoform X1

      UniProtKB/Swiss-Prot
      Q5F499
      UniProtKB/TrEMBL
      A0A1D5PM27
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5F499.1 GenPept UniProtKB/Swiss-Prot:Q5F499

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.