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    LYN LYN proto-oncogene, Src family tyrosine kinase [ Ochotona princeps (American pika) ]

    Gene ID: 101531240, updated on 11-Apr-2024

    Summary

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    Gene symbol
    LYN
    Gene description
    LYN proto-oncogene, Src family tyrosine kinase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ochotona princeps
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 9
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_07 current mOchPri1.hap1 (GCF_030435755.1) 9 NC_080840.1 (43740406..43866173)
    102 previous assembly OchPri4.0 (GCF_014633375.1) 3 NC_050538.1 (37385887..37520555, complement)

    Chromosome 9 - NC_080840.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 68 Neighboring gene trimethylguanosine synthase 1 Neighboring gene small nucleolar RNA U54 Neighboring gene ribosomal protein S20 Neighboring gene MOS proto-oncogene, serine/threonine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase Lyn
    Names
    v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_030435755.1-RS_2023_07

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOchPri1.hap1

    Genomic

    1. NC_080840.1 Reference mOchPri1.hap1

      Range
      43740406..43866173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004580587.3 → XP_004580644.1  tyrosine-protein kinase Lyn isoform X2

      Conserved Domains (4) summary
      cd10364
      Location:125 → 225
      SH2_Src_Lyn; Src homology 2 (SH2) domain found in Lyn
      cd12004
      Location:67 → 122
      SH3_Lyn; Src homology 3 domain of Lyn Protein Tyrosine Kinase
      cd05072
      Location:239 → 510
      PTKc_Lyn; Catalytic domain of the Protein Tyrosine Kinase, Lyn
      pfam07714
      Location:247 → 497
      Pkinase_Tyr; Protein tyrosine kinase

    2. XM_058668636.1 → XP_058524619.1  tyrosine-protein kinase Lyn isoform X4

    3. XM_058668635.1 → XP_058524618.1  tyrosine-protein kinase Lyn isoform X1

    4. XM_004580589.3 → XP_004580646.2  tyrosine-protein kinase Lyn isoform X3

    Nucleotide Protein
    Heading Accession and Version

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