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    RACK1 receptor for activated C kinase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 327682, updated on 12-Oct-2024

    Summary

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    Official Symbol
    RACK1provided by VGNC
    Official Full Name
    receptor for activated C kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:33676
    See related
    BGD:BT11198; Ensembl:ENSBTAG00000019648
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GNB2L1
    Orthologs
    human mouse all
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    Genomic context

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    See RACK1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (40371008..40375831, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene transfer RNA valine (anticodon CAC) Neighboring gene tripartite motif containing 41 Neighboring gene small nucleolar RNA SNORD96 family Neighboring gene small nucleolar RNA SNORD95 Neighboring gene tripartite motif containing 52 Neighboring gene interferon gamma inducible protein 47 Neighboring gene uncharacterized LOC112447402

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RACK1, a PKC targeting protein, is exclusively localized to basal airway epithelial cells. Slager RE, et al. J Histochem Cytochem, 2008 Jan. PMID 17875659, Free PMC Article
    2. RACK1 is up-regulated in angiogenesis and human carcinomas. Berns H, et al. FASEB J, 2000 Dec. PMID 11099474
    3. Characterization of gene expression profiles in early bovine pregnancy using a custom cDNA microarray. Ishiwata H, et al. Mol Reprod Dev, 2003 May. PMID 12658628
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein kinase C binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in rescue of stalled ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small ribosomal subunit protein RACK1
    Names
    guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
    guanine nucleotide-binding protein subunit beta-2-like 1
    receptor of activated protein C kinase 1
    receptor of activated protein kinase C 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175802.3 → NP_786996.1  small ribosomal subunit protein RACK1

      See identical proteins and their annotated locations for NP_786996.1

      Status: VALIDATED

      Source sequence(s)
      EE233795, EV681623, EV698190, EV789366, EW687929, NKLS02000007
      UniProtKB/Swiss-Prot
      P63243, Q3T0R8
      UniProtKB/TrEMBL
      A0AAF6Z6R8
      Related
      ENSBTAP00000066737.1, ENSBTAT00000086553.2
      Conserved Domains (2) summary
      cd00200
      Location:7 → 311
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:18 → 61
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      40371008..40375831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P63243.3 GenPept UniProtKB/Swiss-Prot:P63243

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