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    pcdh1.L protocadherin 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100191020, updated on 18-Aug-2023

    Summary

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    Official Symbol
    pcdh1.L
    Official Full Name
    protocadherin 1 L homeolog
    Primary source
    Xenbase:XB-GENE-983608
    Locus tag
    XELAEV_18017099mg
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    axpc; pcdh1; PCDH-1
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    Genomic context

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    See pcdh1.L in Genome Data Viewer
    Location:
    chromosome: 3L
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (36055477..36195889)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (23149426..23290128)

    Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108710894 Neighboring gene uncharacterized LOC121401158 Neighboring gene uncharacterized LOC108710895 Neighboring gene matrin 3 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Axial protocadherin is a mediator of prenotochord cell sorting in Xenopus. Kuroda H, et al. Dev Biol, 2002 Apr 15. PMID 11944936
    2. Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis. Yoder MD, et al. Dev Dyn, 2011 Nov. PMID 21960065, Free PMC Article
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AXPC functions in notochord morphogenesis by directing cell-fate decisions rather than cell-cell adhesion.
      Title: Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Clone Names

    • MGC86208

    General protein information

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    Preferred Names
    protocadherin 1 L homeolog; protocadherin-1
    Names
    axial protocadherin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      36055477..36195889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018250560.2 → XP_018106049.1  protocadherin-1 isoform X1

      UniProtKB/TrEMBL
      A0A1L8GX95, A0A974DDA8, Q6AX49

    2. XM_018250566.2 → XP_018106055.1  protocadherin-1 isoform X4

      UniProtKB/TrEMBL
      A0A8J0ULG9, Q6AX49

    3. XM_018250564.2 → XP_018106053.1  protocadherin-1 isoform X3

      UniProtKB/TrEMBL
      A0A8J0UES1, Q6AX49

    4. XM_041586139.1 → XP_041442073.1  protocadherin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8J1MKR7, Q90ZF2
      Conserved Domains (2) summary
      cd11304
      Location:476 → 572
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam08374
      Location:779 → 992
      Protocadherin

    5. XM_018250561.2 → XP_018106050.1  protocadherin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8J1MKR7, Q90ZF2
      Conserved Domains (2) summary
      cd11304
      Location:476 → 572
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam08374
      Location:779 → 992
      Protocadherin

    6. XM_018250562.2 → XP_018106051.1  protocadherin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8J1MKR7, Q90ZF2
      Conserved Domains (2) summary
      cd11304
      Location:476 → 572
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam08374
      Location:779 → 992
      Protocadherin

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001136169.1: Suppressed sequence

      Description
      NM_001136169.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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